Numerous studies on the activation of carbon–fluorine bonds have been reported in recent
years. For example, acyl fluorides have been utilized as versatile reagents for acylation …

Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a
variety of applications, from straightforward chemical synthesis to more advanced functions …

Amines featuring an adjacent stereocenter are important building blocks, and recent years
have seen remarkable growth in methods forming these via prochiral α-amino radical …

Phenolic moieties strongly influence lignin reactivity and physical properties, and thus
accurate quantification of phenolic groups in lignin is a critical analytical chemistry need …

Technology for generating especially important amide and peptide bonds from carboxylic
acids and amines that avoids traditional coupling reagents is described. The 1-pot …

Despite the growing importance of fluorinated organic compounds in pharmaceuticals,
agrochemicals, and materials science, the introduction of fluorine into organic molecules is …

An electrochemical amidation of benzoyl hydrazine/carbazate and primary/secondary amine
as coupling partners via concomitant cleavage and formation of C (sp2)–N bonds has been …

Herein, we explored an unprecedented mild, nonirritating, conveniently available, and
recyclable coupling reagent NDTP, which could activate the carboxylic acids via acyl …

We report the development of a deoxyfluorination protocol using sulfur tetrafluoride (SF4) as
a reagent to prepare organofluorine compounds in continuous flow mode. The method uses …

Acyl fluorides are valuable synthetic intermediates, but in some cases they can be
challenging to handle and difficult to isolate given their susceptibility to degradation. In …