Activated ester containing polymers: opportunities and challenges for the design of functional macromolecules
Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …
research has accentuated the need for modern synthetic tools to develop advanced …
Advances in injectable hydrogel strategies for heart failure treatment
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …
public health problem surpassing cancer and urgently needs to be solved. According to the …
Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction
Z Zheng, Y Tan, Y Li, Y Liu, G Yi, CY Yu… - Journal of Controlled …, 2021 - Elsevier
Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …
related deaths worldwide. Although traditional therapeutic agents including various …
Thermogels: In situ gelling biomaterial
In situ gel delivery systems are preferred over conventional systems due to sustained and
prolonged release action of therapeutic payload onto the targeted site. Thermogel, a form of …
prolonged release action of therapeutic payload onto the targeted site. Thermogel, a form of …
Antifibrotic therapies to control cardiac fibrosis
Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …
An injectable oxygen release system to augment cell survival and promote cardiac repair following myocardial infarction
Oxygen deficiency after myocardial infarction (MI) leads to massive cardiac cell death.
Protection of cardiac cells and promotion of cardiac repair are key therapeutic goals. These …
Protection of cardiac cells and promotion of cardiac repair are key therapeutic goals. These …
Injectable thermogel for 3D culture of stem cells
Thermogel is an aqueous polymer solution that undergoes sol-to-gel transition as the
temperature increases. Cells, growth factors, and signaling molecules can be incorporated …
temperature increases. Cells, growth factors, and signaling molecules can be incorporated …
Ultrasonic-driven electrical signal-iron ion synergistic stimulation based on piezotronics induced neural differentiation of mesenchymal stem cells on FeOOH/PVDF …
R Zhang, S Han, L Liang, Y Chen, B Sun, N Liang… - Nano Energy, 2021 - Elsevier
Neural stem cells (NSCs) are thought to be the best seed cells for neurodegenerative
diseases therapy due to their potential to differentiate into either neurons or glial cells …
diseases therapy due to their potential to differentiate into either neurons or glial cells …
Biodegradable thermogelling polymers: working towards clinical applications
As society ages, aging medical problems such as organ damage or failure among senior
citizens increases, raising the demand for organ repair technologies. Synthetic materials …
citizens increases, raising the demand for organ repair technologies. Synthetic materials …
Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following …
Following myocardial infarction (MI), the destruction of vasculature in the infarcted heart
muscle and progression of cardiac fibrosis lead to cardiac function deterioration …
muscle and progression of cardiac fibrosis lead to cardiac function deterioration …