The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

All life forms have an absolute requirement for metals, as metals play critical roles in
fundamental processes, including osmotic regulation, catalysis, metabolism …

The potent redox activity of copper is required for sustaining life. Mismanagement of its
cellular pools, however, can result in oxidative stress and damage connected to aging …

DNAzymes have enjoyed success as metal ion sensors outside cells. Their susceptibility to
metal‐dependent cleavage during delivery into cells has limited their intracellular …

All living organisms require nutrient minerals for growth and have developed mechanisms to
acquire, utilize, and store nutrient minerals effectively. In the aqueous cellular environment …

Throughout evolution, all organisms have harnessed the redox properties of copper (Cu)
and iron (Fe) as a cofactor or structural determinant of proteins that perform critical functions …

DNAzymes, which are sequences of DNA with catalytic activity, have been demonstrated as
a potential platform for sensing a wide range of metal ions. Despite their significant promise …

Copper is an essential metal nutrient that is tightly regulated in the body because loss of its
homeostasis is connected to severe diseases such as Menkes and Wilson diseases …

Since azaacenes have electron-deficient backbones and lone-pair electrons on nitrogen
centers, they can efficiently detect the target molecules or ions through supramolecular …