Promising drug delivery approaches to treat microbial infections in the vagina: A recent update

M Pandey, H Choudhury, A Abdul-Aziz, SK Bhattamisra… - Polymers, 2020 - mdpi.com
An optimal host–microbiota interaction in the human vagina governs the reproductive health
status of a woman. The marked depletion in the beneficial Lactobacillus sp. increases the …

Nanotechnological strategies for systemic microbial infections treatment: A review

MA dos Santos Ramos, KC Dos Santos… - International Journal of …, 2020 - Elsevier
Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug
approaches applied for the rapid and necessary treatment contribute to increase the levels …

Essential Oil of Cymbopogon nardus (L.) Rendle: A Strategy to Combat Fungal Infections Caused by Candida Species

LG De Toledo, MADS Ramos, L Spósito… - International Journal of …, 2016 - mdpi.com
Background: The incidence of fungal infections, especially those caused by Candida yeasts,
has increased over the last two decades. However, the indicated therapy for fungal control …

Chitosan-based drug delivery systems for optimization of photodynamic therapy: a review

GMF Calixto, SR de Annunzio, FD Victorelli… - Aaps Pharmscitech, 2019 - Springer
Drug delivery systems (DDS) can be designed to enrich the pharmacological and
therapeutic properties of several drugs. Many of the initial obstacles that impeded the clinical …

Curcumin-loaded liquid crystalline systems for controlled drug release and improved treatment of vulvovaginal candidiasis

CF Rodero, GM Fioramonti Calixto… - Molecular …, 2018 - ACS Publications
Vulvovaginal candidiasis (VVC) is the most common infection caused by Candida albicans
and greatly reduces the quality of life of women affected by it. Due to the ineffectiveness of …

Engineering resveratrol-loaded chitosan nanoparticles for potential use against Helicobacter pylori infection

L Spósito, D Fonseca, SG Carvalho, RM Sábio… - European Journal of …, 2024 - Elsevier
Helicobacter pylori (H. pylori) is a microorganism directly linked to severe clinical conditions
affecting the stomach. The virulence factors and its ability to form biofilms increase …

[HTML][HTML] In vitro and in vivo anti-Helicobacter pylori activity of Casearia sylvestris leaf derivatives

L Spósito, FB Oda, JH Vieira, FA Carvalho… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance The number of bacterial strains that are resistant to
multiple conventional antimicrobial agents is increasing. In this context, natural products …

Galleria mellonella for systemic assessment of anti-Candida auris using amphotericin B loaded in nanoemulsion

GD Marena, MADS Ramos, LC Lima, M Chorilli… - Science of The Total …, 2022 - Elsevier
Galleria mellonella is a model that uses adult larvae to assess the prophylactic, therapeutic,
and acute toxic potential of substances. Given their benefits, G. mellonella models are being …

Design and characterization of lipid-surfactant-based systems for enhancing topical anti-inflammatory activity of ursolic acid

B Fonseca-Santos, GA Araujo, PS Ferreira… - Pharmaceutics, 2023 - mdpi.com
Skin inflammation is a symptom of many skin diseases, such as eczema, psoriasis, and
dermatitis, which cause rashes, redness, heat, or blistering. The use of natural products with …

Development and characterization of an amphotericin B-loaded nanoemulsion applied to Candida auris biofilms control

GD Marena, MA dos Santos Ramos… - Journal of Drug Delivery …, 2022 - Elsevier
Nanoemulsions (NE) belong to the class of emulsions widely used in the scientific field in
order to improve drugs bioavailability and selectivity, especially in the control of microbial …