An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

Antiviral drug discovery: preparing for the next pandemic

CS Adamson, K Chibale, RJM Goss… - Chemical Society …, 2021 - pubs.rsc.org
Clinically approved antiviral drugs are currently available for only 10 of the more than 220
viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need …

How can nanotechnology help to combat COVID-19? Opportunities and urgent need

EVR Campos, AES Pereira, JL De Oliveira… - Journal of …, 2020 - Springer
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The
most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread …

Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs

DR Tompa, A Immanuel, S Srikanth… - International journal of …, 2021 - Elsevier
The infectious microscopic viruses invade living cells to reproduce themselves, and causes
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …

Untapped potentials of endophytic fungi: A review of novel bioactive compounds with biological applications

MC Manganyi, CN Ateba - Microorganisms, 2020 - mdpi.com
Over the last century, endophytic fungi have gained tremendous attention due to their ability
to produce novel bioactive compounds exhibiting varied biological properties and are …

Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19

F Ahmed, AM Soomro, ARC Salih… - Biomedicine & …, 2022 - Elsevier
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …

Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review

K Mohamed, N Yazdanpanah, A Saghazadeh… - Bioorganic …, 2021 - Elsevier
Background Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak,
there has been an increasing interest in finding a potential therapeutic agent for the disease …

Drug repurposing strategies for COVID-19

SL Senanayake - Future Drug Discovery, 2020 - Taylor & Francis
COVID-19 has now been declared a pandemic and new treatments are urgently needed as
we enter a phase beyond containment. Developing new drugs from scratch is a lengthy …