Engineered extracellular vesicles for cancer therapy
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
[HTML][HTML] Programming assembly of biomimetic exosomes: an emerging theranostic nanomedicine platform
X Xu, L Xu, C Wen, J Xia, Y Zhang, Y Liang - Materials Today Bio, 2023 - Elsevier
Exosomes have emerged as a promising cell-free therapeutic approach. However,
challenges in large-scale production, quality control, and heterogeneity must be overcome …
challenges in large-scale production, quality control, and heterogeneity must be overcome …
Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities
B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …
endogenous characteristics, however, further bioengineering refinement is required to …
Exosomal cargo-loading and synthetic exosome-mimics as potential therapeutic tools
S Li, Z Lin, X Jiang, X Yu - Acta Pharmacologica Sinica, 2018 - nature.com
Exosomes are nano-sized vesicles that serve as mediators for intercellular communication
through the delivery of cargo, including protein, lipids, nucleic acids or other cellular …
through the delivery of cargo, including protein, lipids, nucleic acids or other cellular …
Bioinspired exosome-like therapeutics and delivery nanoplatforms
M Lu, Y Huang - Biomaterials, 2020 - Elsevier
Exosomes have emerged as appealing candidate therapeutic agents and delivery
nanoplatforms due to their endogenous features and unique biological properties. However …
nanoplatforms due to their endogenous features and unique biological properties. However …
Methods of the large-scale production of extracellular vesicles
V Syromiatnikova, A Prokopeva… - International Journal of …, 2022 - mdpi.com
To date, extracellular vesicles (EVs) have been extensively investigated as potential
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …
A comprehensive overview of exosomes as drug delivery vehicles—endogenous nanocarriers for targeted cancer therapy
KB Johnsen, JM Gudbergsson, MN Skov… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
[HTML][HTML] Cell or cell membrane-based drug delivery systems
S Tan, T Wu, D Zhang, Z Zhang - Theranostics, 2015 - ncbi.nlm.nih.gov
Natural cells have been explored as drug carriers for a long period. They have received
growing interest as a promising drug delivery system (DDS) until recently along with the …
growing interest as a promising drug delivery system (DDS) until recently along with the …
Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium
Y Wang, L Zhang, Y Li, L Chen, X Wang, W Guo… - International journal of …, 2015 - Elsevier
Background/objectives Induced pluripotent stem cells (iPS) exhibit enhanced survival and
proliferation in ischemic tissues. However, the therapeutic application of iPS cells is limited …
proliferation in ischemic tissues. However, the therapeutic application of iPS cells is limited …
Bionanoparticles in cancer imaging, diagnosis, and treatment
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …