The road to lysosome‐related organelles: Insights from Hermansky‐Pudlak syndrome and other rare diseases

SL Bowman, J Bi‐Karchin, L Le, MS Marks - Traffic, 2019 - Wiley Online Library
Lysosome‐related organelles (LROs) comprise a diverse group of cell type‐specific,
membrane‐bound subcellular organelles that derive at least in part from the endolysosomal …

Silkworm: a promising model organism in life science

X Meng, F Zhu, K Chen - Journal of Insect Science, 2017 - academic.oup.com
As an important economic insect, silkworm Bombyx mori (L.)(Lepidoptera: Bombycidae) has
numerous advantages in life science, such as low breeding cost, large progeny size, short …

The CRISPR/Cas system mediates efficient genome engineering in Bombyx mori

Y Wang, Z Li, J Xu, B Zeng, L Ling, L You, Y Chen… - Cell research, 2013 - nature.com
Insect genome engineering is crucial for gene functional analysis and the long-term
development of novel pest control technologies. The recently developed engineered …

Ommochromes in invertebrates: biochemistry and cell biology

F Figon, J Casas - Biological Reviews, 2019 - Wiley Online Library
Ommochromes are widely occurring coloured molecules of invertebrates, arising from
tryptophan catabolism through the so‐called Tryptophan→ Ommochrome pathway. They are …

Recent progress in genome engineering techniques in the silkworm, Bombyx mori

T Daimon, T Kiuchi, Y Takasu - Development, growth & …, 2014 - Wiley Online Library
Rapid advances in genome engineering tools, such as zinc finger nucleases (ZFN s),
transcription activator‐like effector nucleases (TALEN s), and the clustered regularly …

Deletion of the Bombyx mori odorant receptor co-receptor (BmOrco) impairs olfactory sensitivity in silkworms

Q Liu, W Liu, B Zeng, G Wang, D Hao… - Insect Biochemistry and …, 2017 - Elsevier
Olfaction plays an essential role in many important insect behaviors such as feeding and
reproduction. To detect olfactory stimuli, an odorant receptor co-receptor (Orco) is required …

Genome editing in the fall armyworm, Spodoptera frugiperda: Multiple sgRNA/Cas9 method for identification of knockouts in one generation

GH Zhu, SCRR Chereddy, JL Howell… - Insect biochemistry and …, 2020 - Elsevier
The CRISPR/Cas9 system is an efficient genome editing method that can be used in
functional genomics research. The fall armyworm, Spodoptera frugiperda, is a serious …

Highly efficient multiplex targeted mutagenesis and genomic structure variation in Bombyx mori cells using CRISPR/Cas9

Y Liu, S Ma, X Wang, J Chang, J Gao, R Shi… - Insect biochemistry and …, 2014 - Elsevier
Bombyx mori is an economically important insect and a model organism for studying
lepidopteran and arthropod biology. Using a highly efficient CRISPR/Cas9 system, we …

Advances in Editing Silkworms (Bombyx mori) Genome by Using the CRISPR-Cas System

GM Baci, AA Cucu, AI Giurgiu, AS Muscă, L Bagameri… - Insects, 2021 - mdpi.com
Simple Summary One of the most powerful gene editing approaches is the CRISPR
(clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) tool …

Advanced technologies for genetically manipulating the silkworm Bombyx mori, a model Lepidopteran insect

H Xu, DA O'Brochta - Proceedings of the Royal Society B …, 2015 - royalsocietypublishing.org
Genetic technologies based on transposon-mediated transgenesis along with several
recently developed genome-editing technologies have become the preferred methods of …