Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However …

Metabolites are the small biological molecules involved in energy conversion and
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …

Corynebacterium glutamicum, Escherichia coli, and Saccharomyces cerevisiae in particular,
have become established as important industrial workhorses in biotechnology. Recent years …

Sample preparation is one of the most important steps in metabolome analysis. The
challenges of determining microbial metabolome have been well discussed within the …

Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …

Metabolomics represents the global assessment of metabolites in a biological sample and
reports the closest information to the phenotype of the biological system under study …

Scale‐up of bioprocesses is hampered by open questions, mostly related to poor mixing and
mass transfer limitations. Concentration gradients of substrate, carbon dioxide, and oxygen …

Metabolomics is a fast‐evolving field that provides qualitative and quantitative analyses of
metabolites within cells, tissues or biofluids. Recent applications of metabolomics …

Measuring metabolic rates by 13C-metabolic flux analysis (13C-MFA) is of central
importance for metabolic engineers and biomedical investigators. Enhanced knowledge of …

We wished to understand the metabolic reprogramming underlying liver fibrosis progression
in mice. Administration to male C57BL/6J mice of the hepatotoxins carbon tetrachloride …