3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …

Subcellular localization of messenger RNAs (mRNAs) can give precise control over where
protein products are synthesized and operate. However, just 10 years ago many in the …

Vimentin intermediate filaments (VIF) extend throughout the rear and perinuclear regions of
migrating fibroblasts, but only nonfilamentous vimentin particles are present in lamellipodial …

Translation is an essential step in gene expression. In this study, we used an improved
SunTag system to label nascent proteins and image translation of single messenger …

Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are
encoded by a large family of differentially expressed genes. Owing in part to their properties …

The diversity of epithelial functions is reflected by the expression of distinct keratin pairs that
are responsible to protect epithelial cells against mechanical stress and to act as signaling …

The formation of protein complexes is crucial to most biological functions. The cellular
mechanisms governing protein complex biogenesis are not yet well understood, but some …

Vimentin, a kind of intermediate filament protein III in mesenchymal cells, has become a
highly researched topic around the world in recent years, as it holds complex biological …

Epithelia are exposed to multiple forms of stress. Keratin intermediate filaments are
abundant in epithelia and form cytoskeletal networks that contribute to cell type–specific …

Subcellular regulation of protein synthesis requires the correct localization of messenger
RNAs (mRNAs) within the cell. In this study, we investigate whether the axonal localization …