Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

Intracellular organelles are subsystems within a cell, whose activity and chemical
composition reflect the metabolic state of live cells. Alterations in cellular homeostasis …

Recent advances in controlled/living polymerization techniques and highly efficient coupling
chemistries have enabled the facile synthesis of complex polymer architectures with …

Mitochondrial dysfunctions cause numerous human disorders. A platform technology based
on biodegradable polymers for carrying bioactive molecules to the mitochondrial matrix …

Mitochondrial oxidative stress is associated with many neurodegenerative diseases, such as
traumatic brain injury (TBI). Targeted delivery of antioxidants to mitochondria has failed to …

In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

Many diseases originate from alterations at nanoscale levels. Precise drug delivery should
be achieved not only at cell level, but also at organelle level to achieve maximum …

Mitochondria are a novel and promising therapeutic target for diagnosis, treatment and
prevention of a lot of human diseases such as cancer, metabolic diseases and …

Mitochondria, the so‐called 'energy factory of cells' not only produce energy but also
contribute immensely in cellular mortality management. Mitochondrial dysfunctions result in …

Delivering active pharmaceutical agents to disease sites using soft polymeric nanoparticles
continues to be a topical area of research. It is becoming increasingly evident that the …