Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …

In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …

A better understanding of the neural systems underlying impulse control is important for
psychiatry. Although most impulses are motivational or emotional rather than motoric per se …

Impulsivity critically relates to many psychiatric disorders. Given the multifaceted construct
that impulsivity represents, defining core aspects of impulsivity is vital for the assessment …

The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the
important role of the subthalamic nucleus (STN) in regulating behavior. However, this …

Dysfunctions in frontostriatal brain circuits have been implicated in neuropsychiatric
disorders, including those characterized by the presence of repetitive behaviors. We …

Substance use disorders are prevalent and debilitating. Certain behavioral syndromes
('behavioral addictions') characterized by repetitive habits, such as gambling disorder …

Adolescence is a transitional period between childhood and adulthood that encompasses
vast changes within brain systems that parallel some, but not all, behavioral changes …

Objective: To assess factors associated with impulse control disorders (ICDs) in Parkinson
disease (PD) using a multicenter case–control design. Methods: Patients enrolled in the …

The phenomenology of delay discounting (eg shape of the discount function; relation to
mental health) has been reviewed in detail previously, but not its neural substrates. Its …