The role of leukocytes in thrombosis

LL Swystun, PC Liaw - Blood, The Journal of the American …, 2016 - ashpublications.org
In recent years, the traditional view of the hemostatic system as being regulated by a
coagulation factor cascade coupled with platelet activation has been increasingly …

Neutrophil extracellular trap (NET) impact on deep vein thrombosis

TA Fuchs, A Brill, DD Wagner - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
Deep vein thrombosis (DVT) is a major health problem that requires improved prophylaxis
and treatment. Inflammatory conditions such as infection, cancer, and autoimmune diseases …

Nanomedicine platform for targeting activated neutrophils and neutrophil–platelet complexes using an α1-antitrypsin-derived peptide motif

MA Cruz, D Bohinc, EA Andraska, J Alvikas… - Nature …, 2022 - nature.com
Targeted drug delivery to disease-associated activated neutrophils can provide novel
therapeutic opportunities while avoiding systemic effects on immune functions. We created a …

Venous thrombosis

AS Wolberg, FR Rosendaal, JI Weitz, IH Jaffer… - Nature reviews Disease …, 2015 - nature.com
Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary
embolism. VTE is the leading cause of lost disability-adjusted life years and the third leading …

Critical review of mouse models of venous thrombosis

JA Diaz, AT Obi, DD Myers Jr… - … , and vascular biology, 2012 - Am Heart Assoc
Deep vein thrombosis and pulmonary embolism are a significant health care concern,
representing a major source of mortality and morbidity. In order to understand the …

[HTML][HTML] P‐and E‐selectin in venous thrombosis and non‐venous pathologies

M Purdy, A Obi, D Myers, T Wakefield - Journal of Thrombosis and …, 2022 - Elsevier
Venous thromboembolism is a very common and costly health problem worldwide.
Anticoagulant treatment for VTE is imperfect: all have the potential for significant bleeding …

Platelet–leukocyte interactions in cardiovascular disease and beyond

L Totani, V Evangelista - Arteriosclerosis, thrombosis, and vascular …, 2010 - Am Heart Assoc
Platelet–leukocyte interactions define a basic cell process that is characterized by the
exchange of signals between platelets and different types of leukocytes and that bridges 2 …

New players in haemostasis and thrombosis

JE Geddings, N Mackman - Thrombosis and haemostasis, 2014 - thieme-connect.com
The blood coagulation cascade is essential for haemostasis, but excessive activation can
cause thrombosis. Importantly, recent studies have identified factors that contribute to …

Pathophysiology of deep vein thrombosis

S Navarrete, C Solar, R Tapia, J Pereira… - Clinical and …, 2023 - Springer
Deep venous thrombosis is a frequent, multifactorial disease and a leading cause of
morbidity and mortality. Most of the time deep venous thrombosis is triggered by the …

Meta-analysis on the effectiveness of team-based learning on medical education in China

M Chen, C Ni, Y Hu, M Wang, L Liu, X Ji, H Chu… - BMC medical …, 2018 - Springer
Background Team-based learning (TBL) has been adopted as a new medical pedagogical
approach in China. However, there are no studies or reviews summarizing the effectiveness …