Innovative approaches and advances for hair follicle regeneration

W Zheng, CH Xu - ACS Biomaterials Science & Engineering, 2023 - ACS Publications
Pathological hair loss (also known as alopecia) and shortage of hair follicle (HF) donors
have posed an urgent requirement for HF regeneration. With the revelation of mechanisms …

[HTML][HTML] Hair follicle morphogenesis during embryogenesis, neogenesis, and organogenesis

S Park - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Hair follicles are mini organs that repeat the growth and regression cycle continuously.
These dynamic changes are driven by the regulation of stem cells via their multiple niche …

Mpox virus infection and drug treatment modelled in human skin organoids

P Li, ST Pachis, G Xu, R Schraauwen, R Incitti… - Nature …, 2023 - nature.com
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models
that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human …

Bioengineered skin organoids: from development to applications

ZX Hong, ST Zhu, H Li, JZ Luo, Y Yang, Y An… - Military Medical …, 2023 - Springer
Significant advancements have been made in recent years in the development of highly
sophisticated skin organoids. Serving as three-dimensional models that mimic human skin …

Mapping oto-pharyngeal development in a human inner ear organoid model

MR Steinhart, WH van der Valk, D Osorio… - …, 2023 - journals.biologists.com
Inner ear development requires the coordination of cell types from distinct epithelial,
mesenchymal and neuronal lineages. Although we have learned much from animal models …

Advanced In Vitro Three-Dimensional Skin Models of Atopic Dermatitis

HJ Jang, JB Lee, JK Yoon - Tissue Engineering and Regenerative …, 2023 - Springer
Atopic dermatitis (AD) is one of the most prevalent inflammatory skin diseases that is
characterized by eczematous rashes, intense itching, dry skin, and sensitive skin. Although …

[HTML][HTML] iPSC-based approach for human hair follicle regeneration

C Vatanashevanopakorn… - Frontiers in Cell and …, 2023 - frontiersin.org
Hair follicles are a multifunctional structure involved in physical protection, thermoregulation,
sensational detection and wound healing. Formation and cycling of hair follicles requires …

How developmental cell atlases inform stem cell embryo models

M Haniffa, A Maartens, SA Teichmann - Nature Methods, 2023 - nature.com
How developmental cell atlases inform stem cell embryo models | Nature Methods Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

[HTML][HTML] Differentiation of pluripotent stem cells for modeling human skin development and potential applications

F Oceguera-Yanez, A Avila-Robinson… - Frontiers in Cell and …, 2022 - frontiersin.org
The skin of mammals is a multilayered and multicellular tissue that forms an environmental
barrier with key functions in protection, regulation, and sensation. While animal models have …

Modelling inner ear development and disease using pluripotent stem cells–a pathway to new therapeutic strategies

K Connolly… - Disease Models & …, 2022 - journals.biologists.com
The sensory epithelia of the mammalian inner ear enable sound and movement to be
perceived. Damage to these epithelia can cause irreversible sensorineural hearing loss and …