Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …

Vaccines are one of the most successful medical inventions to enable the eradication or
control of common and fatal diseases. Environmental exposure of hosts, including helminth …

Schistosomiasis is a disease caused by parasitic flatworms of the Schistosoma spp., and is
increasingly recognized to alter the immune system, and the potential to respond to …

Schistosomiasis is a potentially lethal parasitic disease that profoundly impacts systemic
immune function in chronically infected hosts through mechanisms that remain unknown …

Background Schistosomiasis, with 250 million people affected, is characterized by its
serious hepatic inflammatory response and fibrosis formation, which could lead to …

Since its early spread in early 2020, the disease caused by the novel Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus Disease 2019 (COVID …

The identification of immune correlates of protection against infectious pathogens will
accelerate the design and optimization of recombinant and subunit vaccines. Systematic …

Although most studies of digenetic trematodes of the family Schistosomatidae dwell on
representatives causing human schistosomiasis, the majority of the 130 identified species of …

Background Schistosomes are highly efficient evaders of human immunity, as evident by
their ability to survive in human blood for years. How they protect themselves against the …

Vaccines are the most effective and feasible way to control pathogen infection. Helminths
have been reported to jeopardize the protective immunity mounted by several vaccines …