Snakebites affect about 1.8 million people annually. The current standard of care involves
antibody-based antivenoms, which can be difficult to access and are generally not effective …

Viral-based cancer therapies have tremendous potential, especially in the context of treating
poorly infiltrated cold tumors. However, in tumors with intact anti-viral interferon (IFN) …

Mammarenaviruses are enveloped RNA viruses that can be associated with rodent-
transmitted diseases in humans. Their virions are composed of a nucleocapsid surrounded …

Lymphocytic choriomeningitis virus (LCMV) is a rodent-borne zoonotic arenavirus that
causes congenital abnormalities and can be fatal for transplant recipients. Using a genome …

Viral vectors are poised to acquire a prominent position in modern medicine and
biotechnology owing to their role as delivery agents for gene therapies, oncolytic agents …

The mammarenavirus lymphocytic choriomeningitis virus (LCMV) is a globally distributed
zoonotic pathogen that can be lethal in immunocompromised patients and can cause severe …

Lymphocytic choriomeningitis virus (LCMV) is a well-studied mammarenavirus that can be
fatal in congenital infections. However, our understanding of LCMV and its interactions with …

The recent uptick in the approval of ex vivo cell therapies highlights the relevance of
lentivirus (LV) as an enabling viral vector of modern medicine. As labile biologics, however …

Understanding the cellular host factors that promote and inhibit viral entry is important for
identifying viral countermeasures. CRISPR whole‐genome screens can be used to rapidly …

Human papilloma virus (HPV) infections are associated with almost all cervical cancers and
to a lower extend also with anogenital or oropharyngeal cancers. HPV proteins expressed in …