[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …
valuable method for identifying elderly people at risk for increased vulnerability, disease …
Subpopulations of extracellular vesicles and their therapeutic potential
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …
years been recognized to convey key messages in the molecular communication between …
Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility
L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …
[HTML][HTML] The female response to seminal fluid
JE Schjenken, SA Robertson - Physiological reviews, 2020 - journals.physiology.org
Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …
Semen proteomics and male infertility
Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …
secretions from the testes and epididymis which are mixed at the time of ejaculation with …
Exosomes and cancer: from molecular mechanisms to clinical applications
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …
Comprehensive proteomics analysis of exosomes derived from human seminal plasma
C Yang, W Guo, W Zhang, J Bian, J Yang, Q Zhou… - …, 2017 - Wiley Online Library
Exosomes are membranous nanovesicles of endocytic origin that carry and transfer
regulatory bioactive molecules and mediate intercellular communication between cells and …
regulatory bioactive molecules and mediate intercellular communication between cells and …
[HTML][HTML] Extracellular vesicles and energy metabolism
KG Ronquist - Clinica chimica acta, 2019 - Elsevier
Glycolytic enzymes are among the most frequently identified proteins in proteomics of
exosomes/extracellular vesicles. This review brings up the possibility that exosomes …
exosomes/extracellular vesicles. This review brings up the possibility that exosomes …
[HTML][HTML] Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation
V Murdica, E Giacomini, A Alteri, A Bartolacci… - Fertility and sterility, 2019 - Elsevier
Objective To characterize in depth and investigate the role of exosomes present in seminal
plasma in affecting parameters underlying sperm activity. Design In vitro experimental study …
plasma in affecting parameters underlying sperm activity. Design In vitro experimental study …
Roles of male reproductive tract extracellular vesicles in reproduction
Extracellular vesicles (EVs) are secreted cell‐derived membrane structures present in all
organisms across animal, bacterial, and plant phyla. These vesicles play important roles in …
organisms across animal, bacterial, and plant phyla. These vesicles play important roles in …