Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

[HTML][HTML] CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches

D Uthayakumar, J Sharma, L Wensing… - Frontiers in Genome …, 2021 - frontiersin.org
The Candida genus encompasses a diverse group of ascomycete fungi that have captured
the attention of the scientific community, due to both their role in pathogenesis and emerging …

Global regulatory roles of the c AMP/PKA pathway revealed by phenotypic, transcriptomic and phosphoproteomic analyses in a null mutant of the PKA catalytic subunit …

C Cao, M Wu, J Bing, L Tao, X Ding, X Liu… - Molecular …, 2017 - Wiley Online Library
The conserved cAMP‐dependent protein kinase (PKA) plays critical roles in the regulation of
morphological transitions and virulence in the human fungal pathogen Candida albicans. It …

A multimodal strategy used by a large c-di-GMP network

KM Dahlstrom, AJ Collins, G Doing… - Journal of …, 2018 - Am Soc Microbiol
The Pseudomonas fluorescens genome encodes more than 50 proteins predicted to be
involved in c-di-GMP signaling. Here, we demonstrated that, tested across 188 nutrients …

[HTML][HTML] Candida albicans and Enterococcus faecalis biofilm frenemies: When the relationship sours

OA Alshanta, K Albashaireh, E McKloud, C Delaney… - Biofilm, 2022 - Elsevier
The opportunistic yeast Candida albicans and lactic acid bacteria Enterococcus faecalis are
frequently co-isolated from various infection sites on the human body, suggesting a common …

Remasking of Candida albicans β-glucan in response to environmental pH is regulated by quorum sensing

F Cottier, S Sherrington, S Cockerill, V del Olmo Toledo… - MBio, 2019 - Am Soc Microbiol
Candida albicans is a commensal yeast of the human gut which is tolerated by the immune
system but has the potential to become an opportunistic pathogen. One way in which C …

[HTML][HTML] Conserved and Divergent Functions of the cAMP/PKA Signaling Pathway in Candida albicans and Candida tropicalis

CJ Lin, YL Chen - Journal of Fungi, 2018 - mdpi.com
Fungal species undergo many morphological transitions to adapt to changing environments,
an important quality especially in fungal pathogens. For decades, Candida albicans has …

[HTML][HTML] Transcriptomic meta-analysis to identify potential antifungal targets in Candida albicans

ZA Hefny, B Ji, IE Elsemman, J Nielsen, P Van Dijck - BMC microbiology, 2024 - Springer
Background Candida albicans is a fungal pathogen causing human infections. Here we
investigated differential gene expression patterns and functional enrichment in C. albicans …

Antifungal activity of polymethyl methacrylate/Si3N4 composites against Candida albicans

G Pezzotti, T Asai, T Adachi, E Ohgitani, T Yamamoto… - Acta Biomaterialia, 2021 - Elsevier
Previous studies using gram-positive and-negative bacteria demonstrated that hydrolysis of
silicon nitride (Si 3 N 4) in aqueous suspensions elutes nitrogen and produces gaseous …

[HTML][HTML] Ras signalling in pathogenic yeasts

DR Pentland, E Piper-Brown, FA Mühlschlegel… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Abstract The small GTPase Ras acts as a master regulator of growth, stress response and
cell death in eukaryotic cells. The control of Ras activity is fundamental, as highlighted by the …