Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Adiposity and risk of thyroid cancer: a systematic review and meta‐analysis

D Schmid, C Ricci, G Behrens, MF Leitzmann - Obesity reviews, 2015 - Wiley Online Library
Thyroid cancer incidence has increased rapidly over time, as has obesity prevalence. A link
between the two appears plausible, but the relation of adiposity to thyroid cancer remains …

The role of the transcription factor nuclear factor-kappa B in thyroid autoimmunity and cancer

C Giuliani, I Bucci, G Napolitano - Frontiers in endocrinology, 2018 - frontiersin.org
Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that is involved in
inflammatory and immune responses, as well as in regulation of expression of many other …

Thyroid autoimmune disorders and cancer

SM Ferrari, P Fallahi, G Elia, F Ragusa, I Ruffilli… - Seminars in cancer …, 2020 - Elsevier
In the last decades, many studies conducted in vitro, and in vivo, have shown that thyroid
autoimmunity and thyroid cancer (TC)(mainly papillary TC) can be concomitant, even if the …

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas

DS Hong, R Kurzrock, JG Supko, X He, A Naing… - Clinical cancer …, 2012 - AACR
Purpose: Bardoxolone methyl, a novel synthetic triterpenoid and antioxidant inflammation
modulator, potently induces Nrf2 and inhibits NF-κB and Janus-activated kinase/STAT …

MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma

L Yip, L Kelly, Y Shuai, MJ Armstrong… - Annals of surgical …, 2011 - Springer
Background Papillary thyroid carcinoma (PTC) has relatively indolent behavior, although
some tumors recur and disseminate to distant sites. The aggressive biological behavior of …

Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins

N Khodabandehlou, S Mostafaei, A Etemadi… - BMC cancer, 2019 - Springer
Background Breast cancer is currently the most common neoplasm diagnosed in women
globally. There is a growing body of evidence to suggest that human papillomavirus (HPV) …

MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN

J Ramirez-Moya, L Wert-Lamas, P Santisteban - Oncogene, 2018 - nature.com
Recent studies have shown that miR-146b is the most upregulated microRNA in thyroid
cancer and has a central role in cancer progression through mechanisms that remain largely …

An update on molecular biology of thyroid cancers

O Omur, Y Baran - Critical reviews in oncology/hematology, 2014 - Elsevier
Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There
are several histological variants such as papillary and follicular thyroid carcinoma. Many …

Breast cancer risk and human papillomavirus infection: a Bradford Hill criteria based evaluation

M Usman, Y Hameed, M Ahmad… - Infectious Disorders …, 2022 - benthamdirect.com
Background: The association between human papillomavirus (HPV) and human breast
cancer (BC) has already been thoroughly studied worldwide with contradictory findings …