Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
[HTML][HTML] Plant-based milk substitutes: Bioactive compounds, conventional and novel processes, bioavailability studies, and health effects
The consumption of plant-based milk substitutes has spread rapidly around the world due to
its numerous positive health effects on the human body. Individuals with cow's milk allergy …
its numerous positive health effects on the human body. Individuals with cow's milk allergy …
[HTML][HTML] Matrix metalloproteinases participation in the metastatic process and their diagnostic and therapeutic applications in cancer
G Gonzalez-Avila, B Sommer… - Critical reviews in …, 2019 - Elsevier
Matrix metalloproteinases (MMPs) participate from the initial phases of cancer onset to the
settlement of a metastatic niche in a second organ. Their role in cancer progression is …
settlement of a metastatic niche in a second organ. Their role in cancer progression is …
[HTML][HTML] Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease
(CVD); however, little is known about the mechanism. Δ 9-tetrahydrocannabinol (Δ 9-THC) …
(CVD); however, little is known about the mechanism. Δ 9-tetrahydrocannabinol (Δ 9-THC) …
Natural products as multidrug resistance modulators in cancer
Cancer is a prominent cause of death globally. Currently, many drugs that are in clinical
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …
[HTML][HTML] Cancer prevention and therapy through the modulation of the tumor microenvironment
SC Casey, A Amedei, K Aquilano, AS Azmi… - Seminars in cancer …, 2015 - Elsevier
Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …
[HTML][HTML] Targeting drug chemo-resistance in cancer using natural products
Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …
[HTML][HTML] The impact of estrogen and estrogen-like molecules in neurogenesis and neurodegeneration: beneficial or harmful?
FA Bustamante-Barrientos… - Frontiers in Cellular …, 2021 - frontiersin.org
Estrogens and estrogen-like molecules can modify the biology of several cell types.
Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of …
Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of …
Natural products for the management and prevention of breast cancer
Among all types of cancer, breast cancer is one of the most challenging diseases, which is
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
Botanicals and their bioactive phytochemicals for women's health
BM Dietz, A Hajirahimkhan, TL Dunlap… - Pharmacological reviews, 2016 - ASPET
Botanical dietary supplements are increasingly popular for women's health, particularly for
older women. The specific botanicals women take vary as a function of age. Younger …
older women. The specific botanicals women take vary as a function of age. Younger …