A consensus meeting was held to determine the best use and interpretation of
electrophysiological data in the diagnosis of ALS. The utility of needle EMG and nerve …

Heterogeneity of motor phenotypes is a clinically well-recognized fundamental aspect of
amyotrophic lateral sclerosis (ALS) and is determined by variability of 3 independent primary …

In the past two decades, structural and functional neuroimaging findings have greatly
modified longstanding notions regarding the pathophysiology of amyotrophic lateral …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder of
the motor neurons in the motor cortex, brainstem and spinal cord. A combination of upper …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder
characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance …

The last 30 years have seen a major advance in the understanding of the clinical and
pathological heterogeneity of amyotrophic lateral sclerosis (ALS), and its overlap with …

Background: Progressive muscular atrophy (PMA) is clinically characterized by signs of
lower motor neuron dysfunction and may evolve into amyotrophic lateral sclerosis (ALS) …

Diagnosis, stratification and monitoring of disease progression in amyotrophic lateral
sclerosis currently rely on clinical history and examination. The phenotypic heterogeneity of …

Introduction: Numerous methods for motor unit number estimation (MUNE) have been
developed. The objective of this article is to summarize and compare the major methods and …