Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

Inherent limitations of the traditional approaches to study brain function and disease, such
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …

Increased secretion of hyaluronic acid (HA), a glycosaminoglycan abundant in the brain
extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) …

Despite the wide variety of existing therapies, multiple myeloma (MM) remains a disease
with dismal prognosis. Choosing the right treatment for each patient remains one of the …

Originating in the brain, glioblastoma (GBM) is a highly lethal and virtually incurable cancer,
in large part because it readily develops resistance to treatments. While numerous studies …

Glioblastoma (GBM) resection and medication treatment are limited, and local drug
therapies are required. This study aims to create a hybrid system comprising liposome-like …

Abstract Three-dimensional (3D) ovarian follicle culture offers a promising option for fertility
preservation in patients who cannot receive ovarian tissue transplantation. Our research …

While hyaluronic acid (HA)-based hydrogels have been used clinically for decades, the
mechanisms by which HA exerts molecular weight-dependent bioactivity and how chemical …

Glioblastoma stem cells (GSCs) play an important role in the invasive nature of glioblastoma
(GBM); yet, the mechanisms driving this behavior are poorly understood. To recapitulate …