G protein Gβγ subunits are key mediators of G protein-coupled receptor (GPCR) signaling
under physiological and pathological conditions; their inhibitors have been tested for the …

G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an
array of functions. Mutations in these receptors lead to a number of genetic diseases …

G protein-coupled receptors (GPCRs) constitute the largest superfamily of plasma
membrane signaling proteins. However, virtually nothing is known about their recruitment to …

Ufmylation is implicated in multiple cellular processes, but little is known about its functions
and regulation in protein trafficking. Here, we demonstrate that the genetic depletion of core …

ABSTRACT G protein-coupled receptors (GPCRs) constitute the largest superfamily of cell
surface signaling proteins that share a common structural topology. When compared with …

Here, we present a protocol for visualization and quantification of the recruitment of newly
synthesized G protein-coupled receptors (GPCRs) to coat protein complex II vesicles and …

The α2-adrenoceptor (α2-AR) family comprises α2A-, α2B-and α2C-AR subtypes [1-3],
which are expressed in presynaptic membranes of adrenergic neurons, where they act as …