Arylglyoxals in synthesis of heterocyclic compounds
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …
Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …
they are of immense importance not only both biologically and industrially but also to the …
1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications
A Donaire-Arias, AM Montagut, R Puig de la Bellacasa… - Molecules, 2022 - mdpi.com
Pyrazolo [3, 4-b] pyridines are a group of heterocyclic compounds presenting two possible
tautomeric forms: the 1 H-and 2 H-isomers. More than 300,000 1 H-pyrazolo [3, 4-b] …
tautomeric forms: the 1 H-and 2 H-isomers. More than 300,000 1 H-pyrazolo [3, 4-b] …
Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines
VV Dotsenko, DS Buryi, DY Lukina… - Russian Chemical …, 2020 - Springer
Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines
| Russian Chemical Bulletin Skip to main content SpringerLink Account Menu Find a journal …
| Russian Chemical Bulletin Skip to main content SpringerLink Account Menu Find a journal …
Chemistry of α-oxoesters: a powerful tool for the synthesis of heterocycles
B Eftekhari-Sis, M Zirak - Chemical reviews, 2015 - ACS Publications
Heterocycles are an important class of organic compounds accounting for nearly one-third of
the past decade's publications, which are in the field of heterocyclic chemistry. In fact, two …
the past decade's publications, which are in the field of heterocyclic chemistry. In fact, two …
Discovery of potent and broad-spectrum pyrazolopyridine-containing antivirals against enteroviruses D68, A71, and coxsackievirus B3 by targeting the viral 2C protein
Y Hu, N Kitamura, R Musharrafieh… - Journal of medicinal …, 2021 - ACS Publications
The enterovirus genus of the picornavirus family contains many important human
pathogens. EV-D68 primarily infects children, and the disease manifestations range from …
pathogens. EV-D68 primarily infects children, and the disease manifestations range from …
Synthesis and Structure–activity relationship (SAR) studies of novel pyrazolopyridine derivatives as inhibitors of enterovirus replication
Y Xing, J Zuo, P Krogstad, ME Jung - Journal of Medicinal …, 2018 - ACS Publications
A series of novel pyrazolopyridine compounds have been designed and prepared by a
general synthetic route. Their activities against the replication of poliovirus-1, EV-A71, and …
general synthetic route. Their activities against the replication of poliovirus-1, EV-A71, and …
First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline
S Mahmood, M Lozano Gonzalez… - Journal of Medicinal …, 2023 - ACS Publications
Phosphodiesterase 11A4 (PDE11A4) is a dual-acting cyclic nucleotide hydrolase expressed
in neurons in the CA1, subiculum, amygdalostriatal transition area and …
in neurons in the CA1, subiculum, amygdalostriatal transition area and …
Camphorsulfonic acid catalyzed one-pot three-component reaction for the synthesis of fused quinoline and benzoquinoline derivatives
A simple and an efficient one-pot three-component reaction of arylamines, aromatic
aldehydes, and cyclic ketones was described for the synthesis of various fused quinoline …
aldehydes, and cyclic ketones was described for the synthesis of various fused quinoline …
Design, synthesis, theoretical study, antioxidant, and anticholinesterase activities of new pyrazolo-fused phenanthrolines
E Polo-Cuadrado, C Rojas-Peña, K Acosta-Quiroga… - RSC …, 2022 - pubs.rsc.org
Pyrazole-fused phenanthroline compounds were obtained through several synthetic routes.
NMR, HRMS, and IR techniques were used to characterize and confirm the chemical …
NMR, HRMS, and IR techniques were used to characterize and confirm the chemical …