The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

[HTML][HTML] A review of chemical defense in harlequin toads (Bufonidae: Atelopus)

KC Pearson, RD Tarvin - Toxicon: X, 2022 - Elsevier
Toads of the genus Atelopus are chemically defended by a unique combination of
endogenously synthesized cardiotoxins (bufadienolides) and neurotoxins which may be …

Beyond single host, single parasite interactions: Quantifying competence for complete multi‐host, multi‐parasite communities

TE Stewart Merrill, DM Calhoun… - Functional …, 2022 - Wiley Online Library
Understanding parasite transmission in communities requires knowledge of each species'
capacity to support transmission. This property,'competence', is a critical currency for …

Of poisons and parasites—the defensive role of tetrodotoxin against infections in newts

PTJ Johnson, DM Calhoun, AN Stokes… - Journal of Animal …, 2018 - Wiley Online Library
Classical research on animal toxicity has focused on the role of toxins in protection against
predators, but recent studies suggest these same compounds can offer a powerful defense …

Convergent and parallel evolution in a voltage-gated sodium channel underlies TTX-resistance in the greater blue-ringed octopus: Hapalochlaena lunulata

SL Geffeney, BL Williams, JJC Rosenthal, MA Birk… - Toxicon, 2019 - Elsevier
The natural history and pharmacology of tetrodotoxin (TTX) has long intrigued biologists.
This toxin has a remarkable distribution that spans two domains of life (Bacteria and …

The influence of landscape and environmental factors on ranavirus epidemiology in a California amphibian assemblage

BJ Tornabene, AR Blaustein, CJ Briggs… - Freshwater …, 2018 - Wiley Online Library
A fundamental goal of disease ecology is to determine the landscape and environmental
processes that drive disease dynamics at different biological levels to guide management …

Putting infection on the map: Using heatmaps to characterise within-and between-host distributions of trematode metacercariae

DM Calhoun, J Curtis, C Hassan… - Journal of …, 2023 - cambridge.org
The location of parasites within individual hosts is often treated as a static trait, yet many
parasite species can occur in multiple locations or organs within their hosts. Here, we apply …

Effects of a cyanobacterial toxin on trematode cercariae

M Milotic, D Milotic, J Koprivnikar - Journal of Parasitology, 2019 - meridian.allenpress.com
Eutrophication of aquatic habitats has become a global problem, with implications for host–
parasite dynamics. Blooms of certain cyanobacteria are associated with cyanotoxins …

[HTML][HTML] Are Pacific Chorus Frogs (Pseudacris regilla) Resistant to Tetrodotoxin (TTX)? Characterizing Potential TTX Exposure and Resistance in an Ecological Associate of …

KO Montana, V Ramírez-Castañeda… - Journal of …, 2023 - meridian.allenpress.com
Animals that frequently encounter toxins often develop mechanisms of toxin resistance over
evolutionary time. Both predators that consume toxic prey and organisms in physical contact …

Resistance and tolerance: A hierarchical framework to compare individual versus family-level host contributions in an experimental amphibian-trematode system

WE Stutz, DM Calhoun, PTJ Johnson - Experimental parasitology, 2019 - Elsevier
Hosts have two general strategies for mitigating the fitness costs of parasite exposure and
infection: resistance and tolerance. The resistance-tolerance framework has been well …