This review discusses current understanding of the role that endogenous and exogenous
progenitor cells may have in the treatment of the diseased heart. In the last several years, a …

Despite having access to embryonic stem cells, many laboratories choose to study adult
stem cells, not because of philosophical reasons but because of the practical aspects and …

Mesenchymal stem cells (MSCs) are multipotent cells found in several adult tissues.
Transplanted allogeneic MSCs can be detected in recipients at extended time points …

We describe the isolation of a nonhematopoietic (CD45−, CD34−, SH2+, SH3+, Thy‐1+,
CD44+) human umbilical cord perivascular (HUCPV) cell population. Each HUCPV cell …

Mesenchymal stem cells (MSCs) isolated from bone marrow (BM), cartilage, and adipose
tissue (AT) possess the capacity for self-renewal and the potential for multilineage …

OBJECTIVES: Cell therapy may offer novel therapeutic options for chronic ischemic heart
disease. In a clinical trial, we first assessed the feasibility and safety of intramyocardial …

Repair of the heart is an old dream of physicians caring for patients with cardiac disease.
Experimental studies suggest that cardiac transfer of stem and progenitor cells can have a …

Background Cell transplantation offers a potential therapeutic approach to the repair and
regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI) …

In the absence of effective endogenous repair mechanisms after cardiac injury, cell-based
therapies have rapidly emerged as a potential novel therapeutic approach in ischaemic …

Abstract Up to 2.8× 10 7 fibroblast-like cells displaying an abundant presence of
mesenchymal stem cell (MSC) markers CD73, CD90, CD105 and a low level of HLA-I …