[HTML][HTML] Design of experiments (DoE) applied to pharmaceutical and analytical quality by design (QbD)
IM Fukuda, CFF Pinto, CS Moreira… - Brazilian journal of …, 2018 - SciELO Brasil
According to Quality by Design (QbD) concept, quality should be built into product/method
during pharmaceutical/analytical development. Usually, there are many input factors that …
during pharmaceutical/analytical development. Usually, there are many input factors that …
Genipin-cross-linked hydrogels based on biomaterials for drug delivery: A review
Y Yu, S Xu, S Li, H Pan - Biomaterials science, 2021 - pubs.rsc.org
Genipin is a naturally occurring nontoxic cross-linker, which has been widely used for drug
delivery due to its excellent biocompatibility, admirable biodegradability and stable cross …
delivery due to its excellent biocompatibility, admirable biodegradability and stable cross …
[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …
to have a tremendous impact to offer better health facilities. In this context, medical …
[HTML][HTML] Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of …
Conventional oral therapy of lymphatic filariasis drugs is only effective to kill microfilariae in
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …
Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …
the pharmaceutical industry with the development of novel drug delivery systems that …
Mucoadhesive nanostructured lipid carriers as a cannabidiol nasal delivery system for the treatment of neuropathic pain
AP Matarazzo, LMS Elisei, FC Carvalho… - European Journal of …, 2021 - Elsevier
The therapeutic potential of cannabidiol (CBD) has been explored to treat several
pathologies, including those in which pain is prevalent. However, the oral bioavailability of …
pathologies, including those in which pain is prevalent. However, the oral bioavailability of …
Quality by design (QbD) approaches in current pharmaceutical set-up
ABSTRACT Introduction: Quality by design (QbD) encourages the pharmaceutical industry
to use risk management and science-based manufacturing principles to gain process and …
to use risk management and science-based manufacturing principles to gain process and …
Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: a review
Limited permeability through the stratum corneum (SC) is a major obstacle for numerous
skin care products. One promising approach is to use lipid nanoparticles as they not only …
skin care products. One promising approach is to use lipid nanoparticles as they not only …
Double optimization of rivastigmine-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach: formulation …
Rivastigmine is a drug commonly used in the management of Alzheimer's disease that
shows bioavailability problems. To overcome this, the use of nanosystems, such as …
shows bioavailability problems. To overcome this, the use of nanosystems, such as …
Solid lipid nanoparticles: a promising nanomaterial in drug delivery
K Rajpoot - Current pharmaceutical design, 2019 - ingentaconnect.com
The solid lipid nanoparticles (SLNs) usually consists of active drug molecules along with
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …