[HTML][HTML] Design of experiments (DoE) applied to pharmaceutical and analytical quality by design (QbD)

IM Fukuda, CFF Pinto, CS Moreira… - Brazilian journal of …, 2018 - SciELO Brasil
According to Quality by Design (QbD) concept, quality should be built into product/method
during pharmaceutical/analytical development. Usually, there are many input factors that …

Genipin-cross-linked hydrogels based on biomaterials for drug delivery: A review

Y Yu, S Xu, S Li, H Pan - Biomaterials science, 2021 - pubs.rsc.org
Genipin is a naturally occurring nontoxic cross-linker, which has been widely used for drug
delivery due to its excellent biocompatibility, admirable biodegradability and stable cross …

[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world

M Prasad, UP Lambe, B Brar, I Shah… - Biomedicine & …, 2018 - Elsevier
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

[HTML][HTML] Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of …

AD Permana, IA Tekko, MTC McCrudden… - Journal of controlled …, 2019 - Elsevier
Conventional oral therapy of lymphatic filariasis drugs is only effective to kill microfilariae in
the bloodstream, but is often ineffective to kill adult filarial (macrofilariae) in the complex …

Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Mucoadhesive nanostructured lipid carriers as a cannabidiol nasal delivery system for the treatment of neuropathic pain

AP Matarazzo, LMS Elisei, FC Carvalho… - European Journal of …, 2021 - Elsevier
The therapeutic potential of cannabidiol (CBD) has been explored to treat several
pathologies, including those in which pain is prevalent. However, the oral bioavailability of …

Quality by design (QbD) approaches in current pharmaceutical set-up

V Mishra, S Thakur, A Patil, A Shukla - Expert opinion on drug …, 2018 - Taylor & Francis
ABSTRACT Introduction: Quality by design (QbD) encourages the pharmaceutical industry
to use risk management and science-based manufacturing principles to gain process and …

Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: a review

D Khater, H Nsairat, F Odeh, M Saleh, A Jaber… - Cosmetics, 2021 - mdpi.com
Limited permeability through the stratum corneum (SC) is a major obstacle for numerous
skin care products. One promising approach is to use lipid nanoparticles as they not only …

Double optimization of rivastigmine-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach: formulation …

S Cunha, CP Costa, JA Loureiro, J Alves, AF Peixoto… - Pharmaceutics, 2020 - mdpi.com
Rivastigmine is a drug commonly used in the management of Alzheimer's disease that
shows bioavailability problems. To overcome this, the use of nanosystems, such as …

Solid lipid nanoparticles: a promising nanomaterial in drug delivery

K Rajpoot - Current pharmaceutical design, 2019 - ingentaconnect.com
The solid lipid nanoparticles (SLNs) usually consists of active drug molecules along with
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …