Polyprotein synthesis: a journey from the traditional pre-translational method to modern post-translational approaches for single-molecule force spectroscopy

V Kaur, S Garg, S Rakshit - Chemical Communications, 2023 - pubs.rsc.org
Polyproteins, an array of protein units of similar or differential functions in tandem, have
been extensively utilized by organisms, unicellular or multicellular, as concentrators of the …

Instantaneous splicing and excision of inteins to synthesize polyproteins on a substrate with tunable linkers

V Kaur, S Garg, S Rakshit - Soft Matter, 2022 - pubs.rsc.org
Nature has adapted chimeric polyproteins to achieve superior and multiplexed functionality
in a single protein. However, the hurdles in in vitro synthesis have restricted the biomimicry …

[PDF][PDF] downloaded from the King's Research Portal at https://kclpure. kcl. ac. uk/portal

T Weston - 2023 - kclpure.kcl.ac.uk
Giant modular sarcomeric proteins such as titin have come under increasing scrutiny for
their contributions to diseases such as skeletal and cardiac myopathies. Many variants in …

[PDF][PDF] Understanding the mechanical properties of the Staphylococcus aureus biofilm-associated protein, SasG

AJE Bruce - 2022 - etheses.whiterose.ac.uk
In 1675 Antonie van Leeuwenhoek, a Dutch cloth merchant, ground glass lenses to
construct a magnifying lens for examining weaves of cloth. Upon looking at a sample of rain …