CSC radioresistance: a therapeutic challenge to improve radiotherapy effectiveness in cancer
MA Olivares-Urbano, C Griñán-Lisón, JA Marchal… - Cells, 2020 - mdpi.com
Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …
approximately 50% of all cancer patients either alone or in combination with other treatment …
Cancer stem cells: The root of tumor recurrence and metastases
C Peitzsch, A Tyutyunnykova, K Pantel… - Seminars in cancer …, 2017 - Elsevier
Metastatic tumors are the cause of more than 90% of cancer related deaths. Metastasis
formation can be considered as a culmination of the Darwinian evolutionary process within …
formation can be considered as a culmination of the Darwinian evolutionary process within …
Molecular markers in glioma
K Ludwig, HI Kornblum - Journal of neuro-oncology, 2017 - Springer
Gliomas are the most malignant and aggressive form of brain tumors, and account for the
majority of brain cancer related deaths. Malignant gliomas, including glioblastoma are …
majority of brain cancer related deaths. Malignant gliomas, including glioblastoma are …
The role of cancer stem cells in radiation resistance
CR Arnold, J Mangesius, II Skvortsova… - Frontiers in …, 2020 - frontiersin.org
Cancer stem cells (CSC) are a distinct subpopulation within a tumor. They are able to self-
renew and differentiate and possess a high capability to repair DNA damage, exhibit low …
renew and differentiate and possess a high capability to repair DNA damage, exhibit low …
Metabolic state of glioma stem cells and nontumorigenic cells
E Vlashi, C Lagadec, L Vergnes… - Proceedings of the …, 2011 - National Acad Sciences
Gliomas contain a small number of treatment-resistant glioma stem cells (GSCs), and it is
thought that tumor regrowth originates from GSCs, thus rendering GSCs an attractive target …
thought that tumor regrowth originates from GSCs, thus rendering GSCs an attractive target …
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
BBS Zhou, H Zhang, M Damelin, KG Geles… - Nature reviews Drug …, 2009 - nature.com
The hypothesis that cancer is driven by tumour-initiating cells (popularly known as cancer
stem cells) has recently attracted a great deal of attention, owing to the promise of a novel …
stem cells) has recently attracted a great deal of attention, owing to the promise of a novel …
Cancer stem cells, cancer cell plasticity and radiation therapy
E Vlashi, F Pajonk - Seminars in cancer biology, 2015 - Elsevier
Since the first prospective identification of cancer stem cells in solid cancers the cancer stem
cell hypothesis has reemerged as a research topic of increasing interest. It postulates that …
cell hypothesis has reemerged as a research topic of increasing interest. It postulates that …
The therapeutic promise of the cancer stem cell concept
Cancer stem cells (CSCs) are a subpopulation of tumor cells that selectively possess tumor
initiation and self-renewal capacity and the ability to give rise to bulk populations of …
initiation and self-renewal capacity and the ability to give rise to bulk populations of …
Radiation resistance: a matter of transcription factors
C Galeaz, C Totis, A Bisio - Frontiers in oncology, 2021 - frontiersin.org
Currently, radiation therapy is one of the standard therapies for cancer treatment. Since the
first applications, the field of radiotherapy has constantly improved, both in imaging …
first applications, the field of radiotherapy has constantly improved, both in imaging …
Radiation‐induced reprogramming of breast cancer cells
C Lagadec, E Vlashi, L Della Donna, C Dekmezian… - Stem …, 2012 - academic.oup.com
Breast cancers are thought to be organized hierarchically with a small number of breast
cancer stem cells (BCSCs) able to regrow a tumor while their progeny lack this ability …
cancer stem cells (BCSCs) able to regrow a tumor while their progeny lack this ability …