Functional topography of the human subthalamic nucleus: relevance for subthalamotomy in Parkinson's disease

R Rodriguez‐Rojas, JA Pineda‐Pardo… - Movement …, 2022 - Wiley Online Library
Background The subthalamic nucleus (STN) is considered a key structure in motor,
behavioral, and emotional control. Although identification of the functional topography of the …

Surgical advances in Parkinson's disease

VS Hvingelby, N Pavese - Current Neuropharmacology, 2024 - ingentaconnect.com
While symptomatic pharmacological therapy remains the main therapeutic strategy for
Parkinson's disease (PD), over the last two decades, surgical approaches have become …

Effect of deep brain stimulation on brain network and white matter integrity in Parkinson's disease

LC Huang, LG Chen, PA Wu, CY Pang… - CNS Neuroscience …, 2022 - Wiley Online Library
Aims The effects of subthalamic nucleus (STN)‐deep brain stimulation (DBS) on brain
topological metrics, functional connectivity (FC), and white matter integrity were studied in …

Magnetic resonance-guided focused ultrasound for movement disorders: clinical and neuroimaging advances

R Martínez-Fernández… - Current Opinion in …, 2020 - journals.lww.com
Neuroimaging developments have helped to increase successful applications of focused
ultrasound as a minimally invasive ablative approach and to understand the mechanisms by …

White matter connectivity of subthalamic nucleus and globus pallidus interna targets for deep brain stimulation

AC DiRisio, JM Avecillas-Chasin, S Platt… - Journal of …, 2023 - thejns.org
OBJECTIVE Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus
pallidus interna (GPi) have differential therapeutic effects for Parkinson's disease (PD) that …

An analysis of clinical outcome and tractography following bilateral anterior capsulotomy for depression

JM Avecillas-Chasin, TA Hurwitz, NM Bogod… - Stereotactic and …, 2020 - karger.com
Introduction: Bilateral anterior capsulotomy (BAC) is an effective surgical procedure for
patients with treatment-resistant major depression (TRMD). In this work, we analyze the …

Modulation of nigrofugal and pallidofugal pathways in deep brain stimulation for Parkinson disease

JM Avecillas-Chasin, CR Honey - Neurosurgery, 2020 - journals.lww.com
BACKGROUND Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well-
established surgical therapy for patients with Parkinson disease (PD). OBJECTIVE To define …

Normative connectomes and their use in DBS

GJB Elias, J Germann, A Loh, A Boutet, A Taha… - Connectomic deep brain …, 2022 - Elsevier
Deep brain stimulation (DBS) is known to both modulate local circuits and impact distributed
brain networks. These networks can be studied in vivo using functional MRI (fMRI) and …

[HTML][HTML] Atlas-independent, N-of-1 tissue activation modeling to map optimal regions of subthalamic deep brain stimulation for Parkinson disease

KA Malaga, JT Costello, KL Chou, PG Patil - NeuroImage: Clinical, 2021 - Elsevier
Background Motor outcomes after subthalamic deep brain stimulation (STN DBS) for
Parkinson disease (PD) vary considerably among patients and strongly depend on …

[HTML][HTML] Phylogenetic reduction of the magnocellular red nucleus in primates and inter-subject variability in humans

M Stacho, AN Häusler, A Brandstetter… - Frontiers in …, 2024 - frontiersin.org
Introduction The red nucleus is part of the motor system controlling limb movements. While
this seems to be a function common in many vertebrates, its organization and circuitry have …