Association of blood pressure with outcomes in acute stroke thrombectomy

K Malhotra, N Goyal, AH Katsanos, A Filippatou… - …, 2020 - Am Heart Assoc
Limited data exist evaluating the effect of blood pressure (BP) on clinical outcomes among
patients with acute ischemic stroke with large vessel occlusion treated with mechanical …

[HTML][HTML] Neutrophils obstructing brain capillaries are a major cause of no-reflow in ischemic stroke

M El Amki, C Glück, N Binder, W Middleham, MT Wyss… - Cell reports, 2020 - cell.com
Despite successful clot retrieval in large vessel occlusion stroke,∼ 50% of patients have an
unfavorable clinical outcome. The mechanisms underlying this functional reperfusion failure …

Intracranial bleeding after reperfusion therapy in acute ischemic stroke

G Charbonnier, L Bonnet, A Biondi, T Moulin - Frontiers in Neurology, 2021 - frontiersin.org
Intracranial hemorrhage is one of the most feared complications following brain infarct.
Ischemic tissues have a natural tendency to bleed. Moreover, the first recanalization trials …

Outcomes of endovascular thrombectomy vs medical management alone in patients with large ischemic cores: a secondary analysis of the optimizing patient's …

A Sarraj, AE Hassan, S Savitz, C Sitton, J Grotta… - JAMA …, 2019 - jamanetwork.com
Importance The efficacy and safety of endovascular thrombectomy (EVT) in patients with
large ischemic cores remains unknown, to our knowledge. Objective To compare outcomes …

Mechanical thrombectomy in patients with acute ischemic stroke and ASPECTS≤ 6: a meta-analysis

F Cagnazzo, I Derraz, C Dargazanli… - Journal of …, 2020 - jnis.bmj.com
Background It is uncertain whether mechanical thrombectomy (MT) increases the probability
of a good outcome (modified Rankin Scale (mRS) 0–2) in patients with Alberta Stroke …

Cerebral edema in patients with large hemispheric infarct undergoing reperfusion treatment: a HERMES meta-analysis

FC Ng, N Yassi, G Sharma, SB Brown, M Goyal… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Whether reperfusion into infarcted tissue exacerbates cerebral
edema has treatment implications in patients presenting with extensive irreversible injury …

Endovascular thrombectomy outcomes with and without intravenous thrombolysis for large ischemic cores identified with CT or MRI

I Derraz, S Moulin, B Gory, M Kyheng, C Arquizan… - Radiology, 2023 - pubs.rsna.org
Background Whether intravenous thrombolysis (IVT) prior to endovascular thrombectomy
(EVT) provides additional benefits in patients with acute ischemic stroke (AIS) and a large …

Thrombectomy in extensive stroke may not be beneficial and is associated with increased risk for hemorrhage

L Meyer, M Bechstein, M Bester, U Hanning… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: This study evaluates the benefit of endovascular treatment (EVT)
for patients with extensive baseline stroke compared with best medical treatment. Methods …

Effect of conscious sedation vs. general anesthesia on outcomes in patients undergoing mechanical thrombectomy for acute ischemic stroke: a prospective …

C Ren, G Xu, Y Liu, G Liu, J Wang, J Gao - Frontiers in Neurology, 2020 - frontiersin.org
Background: Although several studies have compared conscious sedation (CS) with general
anesthesia (GA) in patients undergoing mechanical thrombectomy (MT), there has been no …

Importance of delayed reperfusions in patients with incomplete thrombectomy

A Mujanovic, N Jungi, CC Kurmann, T Dobrocky… - Stroke, 2022 - Am Heart Assoc
Background: There is paucity of data regarding the effects of delayed reperfusion (DR) on
clinical outcomes in patients with incomplete reperfusion following mechanical …