The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications

A Quarteroni, A Manzoni, C Vergara - Acta Numerica, 2017 - cambridge.org
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …

[HTML][HTML] Bridging experiments, models and simulations: an integrative approach to validation in computational cardiac electrophysiology

A Carusi, K Burrage… - American Journal of …, 2012 - journals.physiology.org
Computational models in physiology often integrate functional and structural information
from a large range of spatiotemporal scales from the ionic to the whole organ level. Their …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

M Bucelli, A Zingaro, PC Africa… - … journal for numerical …, 2023 - Wiley Online Library
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

Chaste: an open source C++ library for computational physiology and biology

GR Mirams, CJ Arthurs, MO Bernabeu… - PLoS computational …, 2013 - journals.plos.org
Chaste—C ancer, H eart A nd S oft T issue E nvironment—is an open source C++ library for
the computational simulation of mathematical models developed for physiology and biology …

[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation

F Regazzoni, M Salvador, PC Africa, M Fedele… - Journal of …, 2022 - Elsevier
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …

Verification of cardiac tissue electrophysiology simulators using an N-version benchmark

SA Niederer, E Kerfoot, AP Benson… - … of the Royal …, 2011 - royalsocietypublishing.org
Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …

[图书][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications

A Quarteroni, A Manzoni, C Vergara - 2019 - books.google.com
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

PC Africa, R Piersanti, F Regazzoni, M Bucelli… - BMC …, 2023 - Springer
Background Simulating the cardiac function requires the numerical solution of multi-physics
and multi-scale mathematical models. This underscores the need for streamlined, accurate …

[HTML][HTML] Multipatch isogeometric analysis for electrophysiology: simulation in a human heart

M Bucelli, M Salvador, A Quarteroni - Computer Methods in Applied …, 2021 - Elsevier
In the framework of cardiac electrophysiology for the human heart, we apply multipatch
NURBS-based Isogeometric Analysis for the space discretization of the Monodomain model …