Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Autoimmune diseases (ADs) represent a heterogenous group of complex diseases with
increasing incidence in Western countries and are a major cause of morbidity …

MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

Mesenchymal stem cells (MSCs) are increasingly used as regenerative therapies for
patients in the preclinical and clinical phases of various diseases. However, the main …

Bone regenerative medicine is a clinical approach combining live osteoblast progenitors,
such as mesenchymal stromal cells (MSCs), with a biocompatible scaffold that can integrate …

Research has advanced considerably since the first clinical trial of human mesenchymal
stem cells (MSCs) in the early 1990s. During this period, our understanding of MSC biology …

Liver transplantation is the only effective treatment for end-stage liver disease. Currently, the
shortage of high-quality donors has led to the exploration of the use of marginal organs …

Spinal cord injury is an intricate process involving a series of multi-temporal and multi-
component pathological events, among which inflammatory response is the core. Thus, it is …

Featured Application Biomedical product development from PEF application into platelets.
Abstract Nowadays, the standard media used in clinical-scale mesenchymal stem cell …

Haematopoietic microenvironmental niches have been described as the 'gatekeepers' for
the blood and immune systems. These niches change during ontogeny, with the bone …