[HTML][HTML] Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing

S Zhang, J Shen, D Li, Y Cheng - Theranostics, 2021 - ncbi.nlm.nih.gov
CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

The role of ligands in the chemical synthesis and applications of inorganic nanoparticles

A Heuer-Jungemann, N Feliu, I Bakaimi… - Chemical …, 2019 - ACS Publications
The design of nanoparticles is critical for their efficient use in many applications ranging from
biomedicine to sensing and energy. While shape and size are responsible for the properties …

Ratiometric optical nanoprobes enable accurate molecular detection and imaging

X Huang, J Song, BC Yung, X Huang… - Chemical Society …, 2018 - pubs.rsc.org
Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

An overview of nanoparticles commonly used in fluorescent bioimaging

OS Wolfbeis - Chemical Society Reviews, 2015 - pubs.rsc.org
This article gives an overview of the various kinds of nanoparticles (NPs) that are widely
used for purposes of fluorescent imaging, mainly of cells and tissues. Following an …

Gold nanoparticles for in vitro diagnostics

W Zhou, X Gao, D Liu, X Chen - Chemical reviews, 2015 - ACS Publications
IVD test is a crucial component of clinical care that performs a diagnostic test on biological
samples that have been taken from a living body, such as blood, urine, and tissue.(1) Such …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Colloidal nanoparticles as advanced biological sensors

PD Howes, R Chandrawati, MM Stevens - Science, 2014 - science.org
Background Nanoparticle biosensors have the potential to enhance or supersede current
analytical techniques, and their introduction could have a great impact in research and …

Physicochemical properties of nanomaterials: implication in associated toxic manifestations

MA Gatoo, S Naseem, MY Arfat… - BioMed research …, 2014 - Wiley Online Library
Nanotechnology has emerged as one of the leading fields of the science having tremendous
application in diverse disciplines. As nanomaterials are increasingly becoming part of …

Rational engineering of a dynamic, entropy‐driven DNA nanomachine for intracellular microRNA imaging

CP Liang, PQ Ma, H Liu, X Guo… - Angewandte Chemie …, 2017 - Wiley Online Library
We rationally engineered an elegant entropy‐driven DNA nanomachine with three‐
dimensional track and applied it for intracellular miRNAs imaging. The proposed …