Hippocampal neurogenesis continues throughout life and has been suggested to play an
essential role in maintaining spatial cognitive function under physiological conditions. An …

Stroke is a major cause of death and disability worldwide. Yet therapeutic strategies
available to treat stroke are very limited. There is an urgent need to develop novel …

Astrocytes are highly specialized glial cells responsible for trophic and metabolic support of
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …

Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites
lactate and pyruvate toward axons through their expression of monocarboxylate transporter …

A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal
studies have focused on investigating the role of neurons in ASD. However, recent studies …

Schizophrenia is a severe and clinically heterogenous mental disorder affecting
approximately 1% of the population worldwide. Despite tremendous achievements in the …

Schizophrenia is a grave neuropsychiatric disease which frequently onsets between the end
of adolescence and the beginning of adulthood. It is characterized by a variety of …

Depression is a common neurological disease that seriously affects human health. There
are many hypotheses about the pathogenesis of depression, and the most widely …

According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate
transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated …

Fear, anxiety, and trauma-related disorders, including post-traumatic stress disorder (PTSD),
are quite common and debilitating, with an estimated lifetime prevalence of~ 28% in …