The secondary damage that follows central nervous system (CNS) injury is a target for
neuroprotective agents aimed at tissue and function sparing. FK506, a clinically used …

Fission and fusion events dynamically control the shape and function of mitochondria. The
activity of the mitochondrial fission enzyme dynamin-related protein 1 (Drp1) is finely tuned …

Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin
(Nampt/PBEF/visfatin) is an adipocytokine. By synthesizing nicotinamide adenine …

Objective: It is generally agreed that most of the phenomena observed during brain ischemia
and reperfusion can be explained by the damage to membrane structure. Oxidative stress is …

Recent evidence has suggested the neuroprotective effects of physical exercise on cerebral
ischemic injury. However, the role of physical exercise in cerebral ischemia-induced …

Chlorogenic acid (CGA) is known to have antioxidant potentials, yet the effect of CGA on
brain ischemia has not been sufficiently understood. Brain ischemia such as transient global …

Stroke is the most common cause of death among neurological diseases. The protective
effects of Potentilla reptans L. include antioxidative, anti‐inflammatory, and antiapoptotic …

Neuroprotection or prevention of neuronal loss is a complicated molecular process that is
mediated by various cellular pathways. Use of different pharmacological agents as …

Visfatin is a novel adipocytokine with insulin-mimetic effect which plays a role in glucose-
lowering effect of insulin and improves insulin sensitivity. It has been linked to a variety of …

Visfatin, a novel adipokine, is predominantly produced by visceral adipose tissue and it has
been linked to a diverse variety of cellular processes and it is an important factor in cell …