Background Genomic technology can now deliver cost effective, targeted diagnosis and
treatment for patients. Genetic counselling is a communication process empowering patients …

There have been few new therapies for patients with chronic kidney disease in the last
decade. However, the management of patients affected by genetic kidney disease is rapidly …

As genomic science has evolved, so have policy and practice debates about how to
describe and evaluate the ways in which genomic information is treated for individuals …

Purpose Secondary findings are typically offered in an all or none fashion when sequencing
is used for clinical purposes. This study aims to describe the process of offering categorical …

Autonomy plays a central role in bioethics, but there is no consensus as to how we should
understand this concept. This paper critically considers three different conceptions of …

Background Data on the modalities of disclosing genomic secondary findings (SFs) remain
scarce. We explore cancer patients' and the general public's perspectives about disclosing …

Purpose Patients undergoing clinical exome sequencing (ES) are routinely offered the
option to receive secondary findings (SF). However, little is known about the views of …

Objective: The aim of this study was to explore the parental views, attitudes, and preferences
of expanded newborn screening (NBS) through genomic sequencing. Study Design: We …

Purpose Clinically relevant secondary variants were identified in parents enrolled with a
child with developmental delay and intellectual disability. Methods Exome/genome …

Background Pediatric oncology patients are increasingly being offered germline testing to
diagnose underlying cancer predispositions. Meanwhile, as understanding of variant …