Antipsychotic-induced alterations in lipid turnover
S Pereira, E Au, SM Agarwal, DC Wright… - Endocrinology, 2023 - academic.oup.com
Schizophrenia is a debilitating psychiatric disorder that is treated with antipsychotics.
However, despite their efficacy, antipsychotics increase the risk of metabolic disorders in a …
However, despite their efficacy, antipsychotics increase the risk of metabolic disorders in a …
The gut microbiome in schizophrenia and the potential benefits of prebiotic and probiotic treatment
The gut microbiome (GMB) plays an important role in developmental processes and has
been implicated in the etiology of psychiatric disorders. However, the relationship between …
been implicated in the etiology of psychiatric disorders. However, the relationship between …
Adiposity in schizophrenia: a systematic review and meta‐analysis
Objective Although a relationship between schizophrenia (SCZ), antipsychotic (AP)
medication, and metabolic dysregulation is now well established, the effect of adiposity is …
medication, and metabolic dysregulation is now well established, the effect of adiposity is …
Neuropharmacology of organoselenium compounds in mental disorders and degenerative diseases
PT Birmann, AM Casaril, L Abenante… - Current Medicinal …, 2023 - benthamdirect.com
Neurodegenerative and mental disorders are a public health burden with pharmacological
treatments of limited efficacy. Organoselenium compounds are receiving great attention in …
treatments of limited efficacy. Organoselenium compounds are receiving great attention in …
Antipsychotic-induced metabolic syndrome: a review
PS Akinola, I Tardif, J Leclerc - Metabolic Syndrome and Related …, 2023 - liebertpub.com
Schizophrenia, a serious psychiatric disorder, is among the top 10 global causes of disability
and affects nearly 1% of the world population. Antipsychotics constitute the best treatment for …
and affects nearly 1% of the world population. Antipsychotics constitute the best treatment for …
Alternative therapy of psychosis: Potential phytochemicals and drug targets in the management of schizophrenia
Schizophrenia is a chronic mental and behavioral disorder characterized by clusters of
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …
A marked low-grade inflammation and a significant deterioration in metabolic status in first-episode schizophrenia: a five-year follow-up study
M Parksepp, L Haring, K Kilk, E Taalberg, R Kangro… - Metabolites, 2022 - mdpi.com
The objective of this study was to evaluate how schizophrenia spectrum disorders and
applied long-term (5.1 years) antipsychotic (AP) treatment affect the serum level of …
applied long-term (5.1 years) antipsychotic (AP) treatment affect the serum level of …
Shared biological pathways between antipsychotics and omega-3 fatty acids: a key feature for schizophrenia preventive treatment?
Schizophrenia typically emerges during adolescence, with progression from an ultra-high
risk state (UHR) to the first episode of psychosis (FEP) followed by a chronic phase. The …
risk state (UHR) to the first episode of psychosis (FEP) followed by a chronic phase. The …
The expression of immune related genes and potential regulatory mechanisms in schizophrenia
S Yu, Y Qu, Z Du, M Ou, R Lu, J Yuan, Y Jiang… - Schizophrenia …, 2024 - Elsevier
Objective This study aimed to investigate the role of immune dysfunction in the pathogenesis
of schizophrenia through single-cell transcriptome and bulk RNA data analyses. Methods …
of schizophrenia through single-cell transcriptome and bulk RNA data analyses. Methods …
Central insulin dysregulation in antipsychotic-naïve first-episode psychosis: In silico exploration of gene expression signatures
J Lee, X Xue, E Au, WB McIntyre, R Asgariroozbehani… - Psychiatry …, 2024 - Elsevier
Antipsychotic drug (AP)-naïve first-episode psychosis (FEP) patients display premorbid
cognitive dysfunctions and dysglycemia. Brain insulin resistance may link metabolic and …
cognitive dysfunctions and dysglycemia. Brain insulin resistance may link metabolic and …