[HTML][HTML] pH sensitive hydrogels in drug delivery: Brief history, properties, swelling, and release mechanism, material selection and applications

M Rizwan, R Yahya, A Hassan, M Yar, AD Azzahari… - Polymers, 2017 - mdpi.com
Improving the safety efficacy ratio of existing drugs is a current challenge to be addressed
rather than the development of novel drugs which involve much expense and time. The …

Recent advances in natural polymer-based drug delivery systems

X Tong, W Pan, T Su, M Zhang, W Dong, X Qi - Reactive and Functional …, 2020 - Elsevier
Natural polymers have been extensively explored as the vehicles for encapsulation and
delivery of drugs and other bioactive molecules, which have attracted tremendous attention …

Biopolymers and their derivatives: Key components of advanced biomedical technologies

IA Duceac, S Coseri - Biotechnology Advances, 2022 - Elsevier
In the biomedical field, researchers are always looking for novel materials with improved
qualities that may be used in a variety of applications, including pharmaceutical …

Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides

P Zou, X Yang, J Wang, Y Li, H Yu, Y Zhang, G Liu - Food chemistry, 2016 - Elsevier
Chitosan and chitosan oligosaccharides (COS) have been reported to possess various
biomedical properties, including antimicrobial activities, immuno-enhancing effects, and anti …

Antimicrobial hydrogels: A new weapon in the arsenal against multidrug-resistant infections

VWL Ng, JMW Chan, H Sardon, RJ Ono… - Advanced drug delivery …, 2014 - Elsevier
The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an
imminent global public health problem. Treatment with conventional antibiotics often leads …

Recent trends in design and evaluation of chitosan-based colon targeted drug delivery systems: Update 2020

M Kurakula, S Gorityala, K Moharir - Journal of Drug Delivery Science and …, 2021 - Elsevier
Colon-targeted drug delivery systems is an active area of research that is designed to
selectively release the drug in the colonic environment to enhance the oral delivery of active …

Novel amphiphilic chitosan micelles as carriers for hydrophobic anticancer drugs

A Almeida, M Araujo, R Novoa-Carballal… - Materials Science and …, 2020 - Elsevier
Chitosan was grafted with O-methyl-O′-succinylpolyethylene glycol and oleic acid after a
two-step carbodiimide coupling. The structural and physicochemical characterization of the …

Chitin and chitosan from Brazilian Atlantic Coast: Isolation, characterization and antibacterial activity

RM Abdel-Rahman, R Hrdina… - International journal of …, 2015 - Elsevier
Chitin and chitosan were obtained by chemical treatments of shrimp shells. Different particle
sizes (50–1000 μm) of the raw material were used to study their effect on size distribution …

Fabrication and study of curcumin loaded nanoparticles based on folate-chitosan for breast cancer therapy application

S Esfandiarpour-Boroujeni, S Bagheri-Khoulenjani… - Carbohydrate …, 2017 - Elsevier
Purpose of this article is developing novel, inexpensive curcumin loaded chitosan
nanoparticles with targeting ability. Curcumin loaded folate-modified-chitosan-nanoparticles …

The impact of chitooligosaccharides and their derivatives on the in vitro and in vivo antitumor activity: A comprehensive review

X Zhai, C Li, D Ren, J Wang, C Ma… - Carbohydrate Polymers, 2021 - Elsevier
Chitooligosaccharides (COS) are the degraded products of chitin or chitosan. COS is water-
soluble, non-cytotoxic to organisms, readily absorbed through the intestine, and eliminated …