Large-scale genomic investigations have just begun to illuminate the molecular genetic
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …

Sensory processing deficits, first investigated by Kraepelin and Bleuler as possible
pathophysiological mechanisms in schizophrenia, are now being recharacterized in the …

Importance Psychosis-risk studies have examined help-seeking adolescents and young
adults. Population-based studies evaluating psychotic symptoms and neurocognitive …

Our 1992 paper,'The neural substrates of sensorimotor gating of the startle reflex: a review of
recent findings and their implications', reviewed a series of (then) new and preliminary …

Bipolar and schizophrenia network for intermediate phenotypes is a network of investigator-
driven laboratories focused on developing phenotypes, genotypes, and biomarkers for …

Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

The last decade brought tremendous progress in the field of schizophrenia genetics. As a
result of extensive collaborations and multiple technological advances, we now recognize …

Schizophrenia is a form of mental disorder that is behaviorally characterized by abnormal
behavior, such as social function deficits or other behaviors that are disconnected from …

Genome-wide association studies (GWAS) have provided valuable insights into the genetic
basis of complex traits, discovering> 6000 variants associated with> 500 quantitative traits …

α7-Nicotinic acetylcholine receptors have emerged as a potential therapeutic target for the
treatment of neurocognitive dysfunctions in schizophrenia that are often resistant to existing …