Recent advances in α, β-unsaturated carbonyl compounds as mitochondrial toxins
M Hossain, U Das, JR Dimmock - European Journal of Medicinal Chemistry, 2019 - Elsevier
Conjugated α, β-unsaturated ketones are very useful compounds associated with diverse
medicinal properties. This review outlines α, β-unsaturated ketones as candidate cytotoxic …
medicinal properties. This review outlines α, β-unsaturated ketones as candidate cytotoxic …
Diterpenes and their derivatives as potential anticancer agents
MT Islam - Phytotherapy Research, 2017 - Wiley Online Library
As therapeutic tools, diterpenes and their derivatives have gained much attention of the
medicinal scientists nowadays. It is due to their pledging and important biological activities …
medicinal scientists nowadays. It is due to their pledging and important biological activities …
[图书][B] CRC concise encyclopedia of nanotechnology
BI Kharisov, OV Kharissova, U Ortiz-Mendez - 2016 - books.google.com
The book examines the design, application, and utilization of devices, techniques, and
technologies critical to research at the atomic, molecular, and macromolecular levels …
technologies critical to research at the atomic, molecular, and macromolecular levels …
Halimane diterpenoids: sources, structures, nomenclature and biological activities
Covering: 1970 to 2017 Diterpenes with a halimane skeleton constitute a small group of
natural products that can be biogenetically considered as being between labdane and …
natural products that can be biogenetically considered as being between labdane and …
Total synthesis of (−)-3-oxoisotaxodione
SJ Plamondon, JL Gleason - Organic Letters, 2022 - ACS Publications
The first total synthesis of the abietaquinone methide diterpenoid (−)-3-oxoisotaxodione is
reported. The key enabling step is the use of a chiral bicyclic hydrazide as an organocatalyst …
reported. The key enabling step is the use of a chiral bicyclic hydrazide as an organocatalyst …
Diterpenoids of terrestrial origin
JR Hanson - Natural product reports, 2015 - pubs.rsc.org
Covering: January to December 2013. Previous review, Nat. Prod. Rep., 2013, 30, 1346–
1356 This review covers the isolation and chemistry of diterpenoids from terrestrial as …
1356 This review covers the isolation and chemistry of diterpenoids from terrestrial as …
Synthesis and antiproliferative activity of novel dehydroabietic acid-chalcone hybrids
S Grigoropoulou, D Manou, AI Antoniou, A Tsirogianni… - Molecules, 2022 - mdpi.com
Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties,
among others. In the context of this work, DHA was initially modified to two key intermediates …
among others. In the context of this work, DHA was initially modified to two key intermediates …
Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth
D Matias, M Nicolai, L Saraiva, R Pinheiro… - ACS …, 2019 - ACS Publications
Cytotoxicity screenings have identified Plectranthus plants as potential sources of antitumor
lead compounds. In this work, several extracts from Plectranthus madagascariensis were …
lead compounds. In this work, several extracts from Plectranthus madagascariensis were …
Bioactive constituents from transformed root cultures of Nepeta teydea
BM Fraga, A González-Coloma, S Alegre-Gómez… - Phytochemistry, 2017 - Elsevier
A phytochemical study of an extract from transformed root cultures of Nepeta teydea,
induced by Agrobacterium rhizogene s, led to the isolation of the following new compounds …
induced by Agrobacterium rhizogene s, led to the isolation of the following new compounds …
Development and mechanistic insight into the enhanced cytotoxic potential of parvifloron D albumin nanoparticles in EGFR-overexpressing pancreatic cancer cells
Pancreatic cancer is one of the most lethal cancers, with an extremely poor prognosis. The
development of more effective therapies is thus imperative. Natural origin compounds …
development of more effective therapies is thus imperative. Natural origin compounds …