Key Clinical Points Osteoarthritis of the Knee Potential long-term consequences of knee
osteoarthritis include reduced physical activity, deconditioning, impaired sleep, fatigue …

Objective To provide practical principles and examples to help GRADE users make optimal
choices regarding their ratings of certainty of evidence using a minimally or partially …

Including people with or without: Mild to severe osteoarthritis Radiographic evidence of
osteoarthritis i X-ray or MRI changes of arthritis Mechanical symptoms i Locking, clicking …

Importance Clinicians may rely on recommendations from clinical practice guidelines for
management of patients. Observations A clinical practice guideline is a published statement …

Objectives To assess the long-term effects of arthroscopic partial meniscectomy (APM) on
the development of radiographic knee osteoarthritis, and on knee symptoms and function, at …

Importance There is a paucity of high-quality evidence about the long-term effects (ie, 3-5
years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy …

Objectives The objective of the study was to develop an inventory summarizing all anchor-
based minimal important difference (MID) estimates for patient-reported outcome measures …

Objective To assess the benefit of arthroscopic partial meniscectomy (APM) in adults with a
meniscal tear and knee pain in three defined populations (taking account of the comparison …

The treatment of meniscus injuries has recently been facing a paradigm shift toward the field
of tissue engineering, with the aim of regenerating damaged and diseased menisci as …

Knee pain is second only to the back as the most commonly reported area of pain in the
human body. With an overall prevalence of 46.2%, its impact on disability, lost productivity …