Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …

Hypoxia is characterized as insufficient oxygen delivery to tissues and cells in the body and
is prevalent in many human physiology processes and diseases. Thus, it is an attractive …

Sleep disorders have emerged as highly prevalent conditions in the last 50–75 y. Along with
improved understanding of such disorders, the realization that perturbations in sleep …

Sleep apnea (SA) is a very prevalent sleep breathing disorder mainly characterized by
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …

BACKGROUND: Intermittent hypoxia may occur in a number of clinical scenarios, including
interruption of myocardial blood flow or breathing disorders such as obstructive sleep …

Soon after its discovery in the 18th century, oxygen was applied as a therapeutic agent to
treat severely ill patients. Lack of oxygen, commonly termed as hypoxia, is frequently …

Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), plays a critical role in
the pathogenesis of OSA-associated morbidities, especially in the cardiovascular and …

Traditional cell culture is experiencing a revolution moving toward physiomimetic
approaches aiming to reproduce healthy and pathological cell environments as realistically …

Tissue intermittent hypoxia (IH) occurs in obstructive sleep apnea, sickle cell anemia,
physical exercise and other conditions. Poor gas solubility and slow diffusion through culture …

Cyanobacterial blooms represent a significant threat to global water resources because
blooming cyanobacteria deplete oxygen and release cyanotoxins, which cause the mass …