Osteoporosis is a systemic metabolic disease, mainly characterized by reduced bone
mineral density and destruction of bone tissue microstructure. However, the molecular …

Glioma is the most pervasive intracranial tumor in the central nervous system (CNS), with
glioblastoma (GBM) being the most malignant type having a highly heterogeneous cancer …

Background Diabetes mellitus (DM) and periodontitis are two prevalent diseases with
mutual influence. Accumulation of advanced glycation end products (AGEs) in …

Bone mesenchymal stem cells (BMSCs) play an important role in maintaining the dynamic
balance of bone metabolism. Recent studies have reported that a decrease in the …

Introduction Excessive osteoclastogenesis is a key driver of inflammatory bone loss.
Suppressing osteoclastogenesis has always been considered essential for the treatment of …

Alteration of N6-methyladenosine (m6A) is closely linked to spanning biological processes
including osteoporosis (OP) development. This research focuses on the function of …

Cellular senescence is a state of irreversible cellular growth arrest that occurs in response to
various stresses. In addition to exiting the cell cycle, senescent cells undergo many …

The present study aimed to explore the potential roles of the methyltransferase‑like 3
(METTL3)‑mediated methylation of RAS related (RRAS) mRNA in the tumorigenesis and …

Bone development have been shown to play an important role in regulating hematopoiesis
as one major component of bone marrow microenvironment. Recent studies support the …

Excessive bone resorption by osteoclasts results in the development of multiple bone
disorders including osteoporosis. This study aimed to explore the biological function of …