The glial scar and central nervous system repair

JW Fawcett, RA Asher - Brain research bulletin, 1999 - Elsevier
Damage to the central nervous system (CNS) results in a glial reaction, leading eventually to
the formation of a glial scar. In this environment, axon regeneration fails, and remyelination …

Astrocytes in multiple sclerosis: a product of their environment

A Nair, TJ Frederick, SD Miller - Cellular and molecular life sciences, 2008 - Springer
It has long been thought that astrocytes, like other glial cells, simply provide a support
mechanism for neuronal function in the healthy and inflamed central nervous system (CNS) …

[HTML][HTML] The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

P Moshayedi, G Ng, JCF Kwok, GSH Yeo, CE Bryant… - Biomaterials, 2014 - Elsevier
Devices implanted into the body become encapsulated due to a foreign body reaction. In the
central nervous system (CNS), this can lead to loss of functionality in electrodes used to treat …

Schwann cell‐derived exosomes enhance axonal regeneration in the peripheral nervous system

MA Lopez‐Verrilli, F Picou, FA Court - Glia, 2013 - Wiley Online Library
Axonal regeneration in the peripheral nervous system is greatly supported by Schwann cells
(SCs). After nerve injury, SCs dedifferentiate to a progenitor‐like state and efficiently guide …

Cortical cell stiffness is independent of substrate mechanics

J Rheinlaender, A Dimitracopoulos, B Wallmeyer… - Nature materials, 2020 - nature.com
Cortical stiffness is an important cellular property that changes during migration, adhesion
and growth. Previous atomic force microscopy (AFM) indentation measurements of cells …

Cadherin expression and EMT: A focus on gliomas

C Noronha, AS Ribeiro, R Taipa, DS Castro, J Reis… - Biomedicines, 2021 - mdpi.com
Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …

Cadherins in the central nervous system

C Redies - Progress in neurobiology, 2000 - Elsevier
The central nervous system (CNS) is divided into diverse embryological and functional
compartments. The early embryonic CNS consists of a series of transverse subdivisions …

Olfactory ensheathing cells and Schwann cells differ in their in vitro interactions with astrocytes

A Lakatos, RJM Franklin, SC Barnett - Glia, 2000 - Wiley Online Library
Transplanted olfactory ensheathing cells (OECs) are able to remyelinate demyelinated
axons and support regrowth of transected axons after transplantation into the adult CNS …

Injectable thermo-sensitive hydrogel containing ADSC-derived exosomes for the treatment of cavernous nerve injury

S Liu, R Li, K Dou, K Li, Q Zhou, Q Fu - Carbohydrate Polymers, 2023 - Elsevier
Radical pelvic surgery is commonly accompanied by the risk of postoperative erectile
dysfunction induced by cavernous nerve injury (CNI-ED). The strategy of using adipose …

Functions of N‐Acetyl‐l‐Aspartate and N‐Acetyl‐l‐Aspartylglutamate in the Vertebrate Brain: Role in Glial Cell‐Specific Signaling

MH Baslow - Journal of neurochemistry, 2000 - Wiley Online Library
N‐Acetyl‐l‐aspartate (NAA) and its derivative N‐acetylaspartylglutamate (NAAG) are major
osmolytes present in the vertebrate brain. Although they are synthesized primarily in …