The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …

Nitrogen-rich heterocycles, particularly quinazolines and quinazolinones, represent a
unique class of diversified frameworks displaying a broad spectrum of biological functions …

Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …

Two environmentally benign methods for the synthesis of quinazolines via acceptorless
dehydrogenative coupling of 2-aminobenzylamine with benzyl alcohol (Path A) and 2 …

Considerable evidence has been collected indicating that histamine can modulate
proliferation of different normal and malignant cells. High histamine biosynthesis and …

A mild and facile photo-induced cascade radical addition/cyclization of unactivated alkenes
has been reported, through which a variety of biologically valuable phosphine-containing …

Owing to the rapid rise in antibiotic resistance, infectious diseases have become serious
threat to public health. There is an urgent need to develop new antimicrobial agents with …

Many quinazoline derivatives have been synthesized over the last few decades with great
pharmacological potential, such as antimalarial, anti-inflammatory, antimicrobial, anticancer …