Hydrogel-based ocular drug delivery systems: Emerging fabrication strategies, applications, and bench-to-bedside manufacturing considerations
RC Cooper, H Yang - Journal of controlled release, 2019 - Elsevier
The physiological barriers of the eye pose challenges to the delivery of the array of
therapeutics for ocular diseases. Hydrogels have been widely explored for medical …
therapeutics for ocular diseases. Hydrogels have been widely explored for medical …
Hydrogels as emerging materials for cornea wound healing
Hydrogel biomaterials have many favorable characteristics including tuneable mechanical
behavior, cytocompatibility, optical properties suitable for regeneration and restoration of the …
behavior, cytocompatibility, optical properties suitable for regeneration and restoration of the …
Recent advancements in polymeric nanofibers for ophthalmic drug delivery and ophthalmic tissue engineering
Nanofibers due to their unique properties such as high surface-to-volume ratio, porous
structure, mechanical strength, flexibility and their resemblance to the extracellular matrix …
structure, mechanical strength, flexibility and their resemblance to the extracellular matrix …
Propolis-based nanofiber patches to repair corneal microbial keratitis
In this research, polyvinyl-alcohol (PVA)/gelatin (GEL)/propolis (Ps) biocompatible nanofiber
patches were fabricated via electrospinning technique. The controlled release of Propolis …
patches were fabricated via electrospinning technique. The controlled release of Propolis …
Chemical structure-related drug-like criteria of global approved drugs
F Mao, W Ni, X Xu, H Wang, J Wang, M Ji, J Li - Molecules, 2016 - mdpi.com
The chemical structure of a drug determines its physicochemical properties, further
determines its ADME/Tox properties, and ultimately affects its pharmacological activity …
determines its ADME/Tox properties, and ultimately affects its pharmacological activity …
Genipin-crosslinked polyvinyl alcohol/silk fibroin/nano-hydroxyapatite hydrogel for fabrication of artificial cornea scaffolds—a novel approach to corneal tissue …
H Zhou, Z Wang, H Cao, H Hu, Z Luo… - Journal of …, 2019 - Taylor & Francis
Abstract Design of artificial corneal scaffolds substitute is crucial for replacement of impaired
cornea. In this paper, porous polyvinyl alcohol/silk fibroin/nano-hydroxyapatite (PVA/SF/n …
cornea. In this paper, porous polyvinyl alcohol/silk fibroin/nano-hydroxyapatite (PVA/SF/n …
Preparation of Nanoparticle‐Containing Ring‐Implanted Poly (Vinyl Alcohol) Contact Lens for Sustained Release of Hyaluronic Acid
Here, a novel ring‐implanted poly vinyl alcohol (PVA) contact lens (CL) is fabricated and
evaluated as a therapeutic CL with potential of sustained release of hyaluronic acid (HA) …
evaluated as a therapeutic CL with potential of sustained release of hyaluronic acid (HA) …
Reinforced polyaniline/polyvinyl alcohol conducting hydrogel from a freezing–thawing method as self-supported electrode for supercapacitors
In the present work, by using the in situ polymerization of aniline in acidic aqueous solution
of PVA and freezing–thawing method, the reinforced conducting polymer hydrogel of …
of PVA and freezing–thawing method, the reinforced conducting polymer hydrogel of …
3-Chloro-3-methyl-2, 6-diarylpiperidin-4-ones as anti-cancer agents: synthesis, biological evaluation, molecular docking, and in silico ADMET prediction
Piperidine pharmacophore-containing compounds have demonstrated therapeutic efficacy
against a range of diseases and are now being investigated in cancer. A series of 3-chloro-3 …
against a range of diseases and are now being investigated in cancer. A series of 3-chloro-3 …
Interactive deformable electroluminescent devices enabled by an adaptable hydrogel system with optical/photothermal/mechanical tunability
Z Hou, S Zeng, K Shen, PR Healey, HJ Schipper… - Materials …, 2023 - pubs.rsc.org
Deformable electroluminescent devices (DELDs) with mechanical adaptability are promising
for new applications in smart soft electronics. However, current DELDs still present some …
for new applications in smart soft electronics. However, current DELDs still present some …