TH2 cell development and function

JA Walker, ANJ McKenzie - Nature Reviews Immunology, 2018 - nature.com
Abstract T helper 2 (TH 2) cells orchestrate protective type 2 immune responses, such as
those that target helminths and facilitate tissue repair, but also contribute to chronic …

Genetics and epigenetics in asthma

P Ntontsi, A Photiades, E Zervas, G Xanthou… - International journal of …, 2021 - mdpi.com
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

Macrophage polarization and allergic asthma

A Saradna, DC Do, S Kumar, QL Fu, P Gao - Translational Research, 2018 - Elsevier
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through …

SB Fang, HY Zhang, C Wang, BX He… - Journal of …, 2020 - Taylor & Francis
Group 2 innate lymphoid cells (ILC2s) are recently reported to play a more critical role in
allergic diseases. We previously identified that mesenchymal stromal cells (MSCs) elicited …

Small-magnitude effect sizes in epigenetic end points are important in children's environmental health studies: the children's environmental health and disease …

CV Breton, CJ Marsit, E Faustman… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Noncoding RNAs, cytokines, and inflammation‐related diseases

JL Marques‐Rocha, M Samblas, FI Milagro… - The FASEB …, 2015 - Wiley Online Library
Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …

A guide to miRNAs in inflammation and innate immune responses

C Nejad, HJ Stunden, MP Gantier - The FEBS journal, 2018 - Wiley Online Library
The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …

Asthma inflammatory phenotypes show differential microRNA expression in sputum

T Maes, FA Cobos, F Schleich, V Sorbello… - Journal of Allergy and …, 2016 - Elsevier
Background Asthma is classified according to severity and inflammatory phenotype and is
likely to be distinguished by specific microRNA (miRNA) expression profiles. Objective We …

[HTML][HTML] Micro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections

T Abu-Izneid, N AlHajri, AM Ibrahim, MN Javed… - Journal of advanced …, 2021 - Elsevier
Abstract Background Micro-RNAs (miRNAS) are non-coding, small RNAs that have
essential roles in different biological processes through silencing genes, they consist of 18 …