West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe,
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …

Viral Encephalitis Encephalitis is characterized by fever, neurologic deficits, seizures,
pleocytosis, and neuroimaging and EEG abnormalities. The main viral causes segregate …

The determinants of severe disease caused by West Nile virus (WNV) and why only~ 1% of
individuals progress to encephalitis remain poorly understood. Here, we use human and …

Abstract Analysis of immune cell states is paramount to our understanding of the
pathogenesis of a broad range of human diseases. Immunologists rely on fluorescence …

West Nile virus (WNV) infection is an emerging mosquito-borne disease that can lead to
severe neurological illness and currently has no available treatment or vaccine. Using …

West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that
emerged in North America in 1999 in New York City. Over the past 15 years, WNV has …

Many arboviruses, including viruses of the Flavivirus genus, are known to cause severe
neurological disease in humans, often with long-lasting, debilitating sequalae in surviving …

West Nile virus (WNV) is the most important causative agent of viral encephalitis worldwide
and an important public health concern in the United States due to its high prevalence …

Innate immunity, the first line of defense against invading pathogens, is an ancient form of
host defense found in all animals, from sponges to humans. During infection, innate immune …

Infections with dengue virus (DENV), West Nile virus (WNV) and Zika virus (ZIKV) usually
present similar mild symptoms at early stages, and most infections (~ 80%) are …