Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

This review covers briefly the work carried out at our institute (IBCh), in many cases in
collaboration with other Russian and foreign laboratories, for the last 50 years. It discusses …

The hypothesis of N-methyl-D-aspartate receptor (NMDAR) dysfunction for cognitive
impairment in schizophrenia constitutes the theoretical basis for the translational application …

Calcium-activated potassium channels (KCa) are important participants in calcium signaling
pathways due to their ability to be activated by an increase in intracellular free calcium …

Ants are among the most abundant terrestrial invertebrate predators on Earth. To overwhelm
their prey, they employ several remarkable behavioral, physiological, and biochemical …

Honeybees have been helpful insects since ancient centuries, and this benefit is not limited
to being a honey producer only. After the bee stings a person, pain, and swelling occur in …

Here, we introduce the third release of Kalium database (http://kaliumdb. org/), a manually
curated comprehensive depository that accumulates data on polypeptide ligands of …

The therapeutic potential of bee venom-derived peptides, particularly apamin and mellitin, in
cancer treatment has garnered significant attention as a promising avenue for advancing …

Previous studies have identified some key amino acid residues in scorpion toxins blocking
potassium channels. In particular, the most numerous toxins belonging to the α-KTx family …

Cepharanthine, a multitarget alkaloid which has recently been shown to be effective against
SARS-Cov-2, and berbamine, an alkaloid characterized as a calcium channel blocker, both …