[HTML][HTML] Recent developments in inertial and centrifugal microfluidic systems along with the involved forces for cancer cell separation: a review

A Farahinia, W Zhang, I Badea - Sensors, 2023 - mdpi.com
The treatment of cancers is a significant challenge in the healthcare context today.
Spreading circulating tumor cells (CTCs) throughout the body will eventually lead to cancer …

Recent advances in nano/microfluidics-based cell isolation techniques for cancer diagnosis and treatments

N Shanehband, SM Naghib - Biochimie, 2024 - Elsevier
Miniaturization has improved significantly in the recent decade, which has enabled the
development of numerous microfluidic systems. Microfluidic technologies have shown great …

Dynamic tissue model in vitro and its application for assessment of microplastics-induced toxicity to air-blood barrier (ABB)

A Fu, S Mao, N Kasai, H Zhu, H Zeng - Biosensors and Bioelectronics, 2024 - Elsevier
The replication of the hominine physiological environment was identified as an effectual
strategy to develop the physiological model in vitro to perform the intuitionistic assessment of …

Tailoring drug delivery systems by microfluidics for tumor therapy

Q Zhang, G Kuang, L Wang, L Fan, Y Zhao - Materials Today, 2024 - Elsevier
Drug delivery systems (DDSs) for tumor treatment is a specialized method aimed at
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …

[HTML][HTML] Emergent trends in organ-on-a-chip applications for investigating metastasis within tumor microenvironment: A comprehensive bibliometric analysis

C He, F Lu, Y Liu, Y Lei, X Wang, N Tang - Heliyon, 2024 - cell.com
Background With the burgeoning advancements in disease modeling, drug development,
and precision medicine, organ-on-a-chip has risen to the forefront of biomedical research …

[HTML][HTML] Biolayer interferometry and its applications in drug discovery and development

A Jug, T Bratkovič, J Ilaš - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Biolayer interferometry (BLI) is an optical 'dip-and-read'biosensor method for real-time, label-
free analysis of biomolecular interactions. It can be used for kinetic analyses, analyte …

Recent advances in microfluidics by tuning wetting behaviors

Q Zeng, B Wang, Z Guo - Materials Today Physics, 2023 - Elsevier
Wettability and microfluidics are inextricably linked, and the wettability-based approach to
microfluidics exhibits considerable potential. In addition to microfluidics, there has been a …

[HTML][HTML] Numerical approaches for recovering the deformable membrane profile of electrostatic microdevices for biomedical applications

M Versaci, FC Morabito - Sensors, 2023 - mdpi.com
Recently, a circular symmetrical nonlinear stationary 2D differential model for biomedical
micropumps, where the amplitude of the electrostatic field is locally proportional to the …

Know your molecule: pharmacological characterization of drug candidates to enhance efficacy and reduce late-stage attrition

T Kenakin - Nature Reviews Drug Discovery, 2024 - nature.com
Despite advances in chemical, computational and biological sciences, the rate of attrition of
drug candidates in clinical development is still high. A key point in the small-molecule …

Reprogrammable Magnetic Soft Actuators with Microfluidic Functional Modules via Pixel‐Assembly

X Zhao, H Yao, Y Lv, Z Chen, L Dong, J Huang, S Mi - Small, 2024 - Wiley Online Library
Magnetic soft actuators and robots have attracted considerable attention in biomedical
applications due to their speedy response, programmability, and biocompatibility. Despite …